Evidence map›Paper›PMID 29118885›Full record

ArticleCardiology research2017

Mitral Annular Dynamics and Left Ventricular Diastole.

Angel Lopez-Candales, Dagmar F Hernandez-Suarez, Francisco Lopez Menendez

Open access · diamondAbstract read
In one paragraph

Article in Cardiology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Angel Lopez-CandalesCardiovascular Medicine Division, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Dagmar F Hernandez-SuarezDepartment of Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Francisco Lopez MenendezDivision of Cardiovascular Health and Disease, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
University of Puerto Rico System · PRUniversity of Cincinnati Medical Center · US

Funding

Hispanics in Research Capability: SoHP & SOM Partnership (HIREC)S21MD001830 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ELIAS BONETA, AUGUSTO R, ESTAPE, ESTELA S · 2005 to 2010
$30.0M
Hispanic Clinical and Translational Research Education and Career Development ProgramR25MD007607 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Karen G. Martinez Gonzalez, Barbara Segarra-Vazquez · 2012 to 2026
$7.4M
Conduits: MSHS Translational Science HubTL1TR001434 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GABRILOVE, JANICE L · 2015 to 2019
$2.1M
NCATS NIH HHS TL1 TR001434NIMHD NIH HHS R25 MD007607NIMHD NIH HHS S21 MD001830
6 · The paper itself

Abstract

backgroundThough diastolic interrogation of the mitral annulus (MA) using tissue Doppler imaging (TDI) has been quite useful in assessing left ventricular (LV) diastolic function, the relative contribution of the previous cycle MA systolic displacement or velocity components to subsequent LV diastole has not been previously investigated. We therefore sought to determine the association between MA systolic dynamics and LV diastolic function parameters.

methodsFor this retrospective study, only complete echocardiograms having good endocardial border resolution of both left atrial (LA) and LV chambers with M-mode (MAPSE) and tissue Doppler of the lateral MA (MA TDI S') as well as complete Doppler data to perform assessment of LV diastole were included in our analysis.

resultsData from 100 patients (mean age 54 ± 14) showed that both MA systolic displacement and velocity correlate with LV ejection fraction (P < 0.05). Only MA displacement was associated with age and LV mass. Most importantly no correlation was found between MAPSE and LV diastole. However, in sharp contrast MA TDI S' correlated with MA relaxation velocities during both early and late LV diastole.

conclusionEven though MAPSE and MA TDI S' are surrogate measures of LV ejection fraction, only MA TDI S' correlates with diastolic MA velocities as no correlation was identified between MAPSE and measures of LV diastole. Additional studies are now warranted to explore whether a reduced MA TDI S' may affect the symptomatic profile or the overall prognosis of patients with LV diastolic dysfunction.

Indexed as

Diastolic dysfunctionEchocardiographyMitral annulus

Identifiers

PMID29118885
PMCPMC5667710
OpenAlexW2766309898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.