Evidence map›Paper›PMID 29118802›Full record

ArticleInterventional neurology2017

Mechanical Thrombectomy for Middle Cerebral Artery Division Occlusions: A Systematic Review and Meta-Analysis.

Hisham Salahuddin, Aixa Espinosa, Mark Buehler, Sadik A Khuder, Abdur R Khan, Gretchen Tietjen, Syed Zaidi, Mouhammad A Jumaa

Open access · greenAbstract read
In one paragraph

Article in Interventional neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. M1, M2: Time to Bid Adieu!Stroke (Hoboken, N.J.) · 2023
    Review
  3. Intraarterial urokinase for thrombus migration after mechanical thrombectomy for large vessel ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hisham SalahuddinDepartment of Neurology, University of Toledo Medical Center, Toledo, Ohio, USA.
Aixa EspinosaDepartment of Neurology, University of Toledo Medical Center, Toledo, Ohio, USA.
Mark BuehlerDepartment of Radiology, University of Toledo Medical Center, Toledo, Ohio, USA.
Sadik A KhuderDepartment of Medicine and Public Health, University of Toledo Medical Center, Toledo, Ohio, USA.
Abdur R KhanDepartment of Cardiology Division, University of Louisville, Louisville, Kentucky, USA.
Gretchen TietjenDepartment of Neurology, University of Toledo Medical Center, Toledo, Ohio, USA.
Syed ZaidiDepartment of Neurology, University of Toledo Medical Center, Toledo, Ohio, USA.
Mouhammad A JumaaDepartment of Neurology, University of Toledo Medical Center, Toledo, Ohio, USA.
University of Toledo Medical Center · USNeurology, Inc · USUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMiddle cerebral artery division (M2) occlusion was significantly underrepresented in recent mechanical thrombectomy (MT) randomized controlled trials, and the approach to this disease remains heterogeneous.

objectiveTo conduct a systematic review and meta-analysis of outcomes at 90 days among patients undergoing MT for M2 middle cerebral artery (MCA) occlusions.

methodsFive clinical databases were searched from inception through September 2016. Observational studies reporting 90-day modified Rankin Scale scores for patients undergoing MT for M2 MCA occlusions with an M1 MCA control group were selected. The primary outcome of interest was good clinical outcome 90 days after MT of an M1 or M2 MCA occlusion. Secondary outcomes of interest included mortality and excellent clinical outcome, recanalization rates, significant intracerebral hemorrhage, and procedural complications.

resultsA total of 323 publications were identified, and 237 potentially relevant articles were screened. Six studies were included in the analysis (M1 = 1,203, M2 = 258; total

conclusionsMT of M2 MCA occlusions is as safe as that of main trunk MCA occlusions, and comparable in terms of clinical outcomes and hemorrhagic complications. Randomized clinical trials are needed to assess the impact of MT in patients with M2 occlusions, given that M1 MCA occlusions have different natural histories than M2 occlusions.

Indexed as

Cerebrovascular accidentCerebrovascular disease/strokeCerebrovascular proceduresInfarctionIschemic strokeM2 middle cerebral artery occlusionMiddle cerebral arteryMiddle cerebral artery divisionStrokeThrombectomy

Identifiers

PMID29118802
PMCPMC5662958
OpenAlexW2750173691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.