Evidence map›Paper›PMID 29118797›Full record

ArticleInterventional neurology2017

Comparison of Vacuum Pressures and Forces Generated by Different Catheters and Pumps for Aspiration Thrombectomy in Acute Ischemic Stroke.

Michael T Froehler

Registry-linked trialAbstract read
In one paragraph

Article in Interventional neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07231380 (Plunger Stroke Trial), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07231380 narecruitingnot on this mapstarted 2026, after this paper: background citation

Plunger Stroke Trial: A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion Stroke With the Raptor Aspiration Catheter

TypeinterventionalSponsorVanderbilt University Medical CenterRan2026 to 2027Enrolled500ConditionsAcute Ischemic Stroke Patients, Large Vessel OcclusionArmsPlunger Technique, Static Manual Aspiration Thrombectomy
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Comparative analysis of syringes versus pump devices in benchtop aspiration thrombectomy models: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Does endovascular thrombectomy using super-bore 0.088" large distal platform offer advantages over balloon guide catheters in acute ischemic stroke secondary to large vessel occlusion?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Initial experience with ultra-large-bore catheter aspiration for very large vessel occlusions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Initial experience of utilizing a lower-profile transradial approach for mechanical thrombectomy: Comparable efficacy to larger-bore transfemoral approaches.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
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  8. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  9. Review
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  12. In vitro testing of a funnel-tip catheter with different clot types to decrease clot migration in mechanical thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Article
  13. Review
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  18. Preliminary experience with 088 large bore intracranial catheters during stroke thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael T FroehlerCerebrovascular Program, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDirect aspiration thrombectomy is an increasingly utilized technique in endovascular stroke treatment that relies on vacuum and suction force to remove the clot. This report assesses the pressures and forces generated by different catheters and pumps.

methodsVacuum pressures were measured using a vacuum gauge for several catheters (Stryker Catalyst6, Penumbra Ace 064, Medtronic Arc 061, and Penumbra 041) and pumps (Penumbra pump, 60-mL syringe, and the ASPIRE device). Suction forces were calculated based on pressure and catheter tip size (force = area × pressure). Vacuum pressures and forces were also assessed with a coaxial microcatheter (Rebar 18; inner diameter = 0.021 inches), mimicking a combined aspiration and stent retriever approach.

resultsAll catheters transmitted similar vacuum pressures, but suction force was proportionate to catheter tip area. Pump vacuum pressures were also similar, although the Penumbra pump (mean -25.63 inches Hg [inHg]) was slightly weaker than the syringe and the ASPIRE device (-27.04 and -27.58 inHg, respectively;

conclusionsAll catheters transmit similar vacuum pressure, but the suction force on the clot is stronger with larger catheter tips. Coaxial microcatheters will have a minimal impact on suction force as long as they are proximal to the aspiration catheter tip. Currently available thrombectomy suction devices, including the Penumbra pump, the ASPIRE handheld pump, and the 60-mL syringe, all develop similar vacuum pressures.

Indexed as

ADAPTAspiration catheterAspiration thrombectomyMechanical thrombectomyStroke

Identifiers

PMID29118797
PMCPMC5662950

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.