Evidence map›Paper›PMID 29118762›Full record

ArticleFrontiers in immunology2017

LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast

Dimitra Lamprinaki, Gemma Beasy, Aleksandra Zhekova, Alexandra Wittmann, Steve James, Jo Dicks, Yoichiro Iwakura, Shinobu Saijo, Xiaomin Wang, Chung-Wai Chow and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Autophagy and Bacterial infections.Autophagy reports · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. LC3-Associated Phagocytosis in Bacterial Infection.Pathogens (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
  15. Frontiers in cellular and infection microbiology · 2021
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Dimitra LamprinakiFood and Health Institute Strategic Programme, Quadram Institute, Norwich, United Kingdom.
Gemma BeasyFood and Health Institute Strategic Programme, Quadram Institute, Norwich, United Kingdom.
Aleksandra ZhekovaNorwich Medical School, University of East Anglia, Norwich, United Kingdom.
Alexandra WittmannFood and Health Institute Strategic Programme, Quadram Institute, Norwich, United Kingdom.
Steve JamesThe National Collection of Yeast Cultures, Quadram Institute, Norwich, United Kingdom.
Jo DicksThe National Collection of Yeast Cultures, Quadram Institute, Norwich, United Kingdom.
Yoichiro IwakuraCentre for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Shinobu SaijoDepartment of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba, Japan.
Xiaomin WangUniversity of Toronto, University Health Network, Toronto, ON, Canada.
Chung-Wai ChowUniversity of Toronto, University Health Network, Toronto, ON, Canada.
Ian RobertsThe National Collection of Yeast Cultures, Quadram Institute, Norwich, United Kingdom.
Tamas KorcsmarosFood and Health Institute Strategic Programme, Quadram Institute, Norwich, United Kingdom.
Ulrike MayerSchool of Biological Science, University of East Anglia, Norwich, United Kingdom.
Thomas WilemanNorwich Medical School, University of East Anglia, Norwich, United Kingdom.
Norihito KawasakiFood and Health Institute Strategic Programme, Quadram Institute, Norwich, United Kingdom.
Quadram Institute · GBUniversity of East Anglia · GBUniversity of Toronto · CAChiba University · JPEarlham Institute · GBTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human fungal microbiota known as mycobiota is increasingly recognized as a critical factor in human gut health and disease. Non-pathogenic commensal yeasts such as

Indexed as

autophagydendritic celldendritic cell-associated lectin 2fungiLC3-associated phagocytosis

Identifiers

PMID29118762
PMCPMC5661120
OpenAlexW2765156844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.