ArticleInternational journal of nanomedicine2017
Supercritical carbon dioxide-developed silk fibroin nanoplatform for smart colon cancer therapy.
Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Rapid Volumetric Bioprinting of Decellularized Extracellular Matrix Bioinks.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Water soluble curcumin with alkyl sulfonate moiety: Synthesis, and anticancer efficacy.Heliyon · 2024Article
- The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present.Pharmaceutics · 2024Review
- Translational Challenges and Prospective Solutions in the Implementation of Biomimetic Delivery Systems.Pharmaceutics · 2023Review
- Versatile Potential of Photo-Cross-Linkable Silk Fibroin: Roadmap from Chemical Processing Toward Regenerative Medicine and Biofabrication Applications.Biomacromolecules · 2023Review
- Volumetric additive manufacturing of pristine silk-based (bio)inks.Nature communications · 2023Article
- Supercritical Fluids and Nanoparticles in Cancer Therapy.Micromachines · 2022Review
- Curcumin-Based Nanoformulations: A Promising Adjuvant towards Cancer Treatment.Molecules (Basel, Switzerland) · 2022Review
- Prospects of Curcumin Nanoformulations in Cancer Management.Molecules (Basel, Switzerland) · 2022Review
- Research progress of natural silk fibroin and the application for drug delivery in chemotherapies.Frontiers in pharmacology · 2022Review
- Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.Frontiers in cell and developmental biology · 2022Article
- Review
- Antitumoral Activities of Curcumin and Recent Advances to ImProve Its Oral Bioavailability.Biomedicines · 2021Review
- Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers.Biomolecules · 2021Review
- Fibroin nanoparticles: a promising drug delivery system.Drug delivery · 2020Review
- Silk Particles as Carriers of Therapeutic Molecules for Cancer Treatment.Materials (Basel, Switzerland) · 2020Review
- Improving Solubility and Bioavailability of Breviscapine with Mesoporous Silica Nanoparticles Prepared Using Ultrasound-Assisted Solution-Enhanced Dispersion by Supercritical Fluids Method.International journal of nanomedicine · 2020Article
- Enhancing Bioavailability and Stability of Curcumin Using Solid Lipid Nanoparticles (CLEN): A Covenant for Its Effectiveness.Frontiers in bioengineering and biotechnology · 2020Article
- Nanocurcumin: A Promising Candidate for Therapeutic Applications.Frontiers in pharmacology · 2020Review
- Silk fibroin-based nanotherapeutics: application in the treatment of colonic diseases.Nanomedicine (London, England) · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo deliver insoluble natural compounds into colon cancer cells in a controlled fashion. MATERIALS AND
methodsCurcumin (CM)-silk fibroin (SF) nanoparticles (NPs) were prepared by solution-enhanced dispersion by supercritical CO
resultsCM-SF NPs (<100 nm) with controllable particle size were prepared by SEDS. CM-SF NPs had a time-dependent intracellular uptake ability, which led to an improved inhibition effect on colon cancer cells. Interestingly, the anticancer effect of CM-SF NPs was improved, while the side effect on normal human colon mucosal epithelial cells was reduced by a concentration of ~10 μg/mL. The anticancer mechanism involves cell-cycle arrest in the G
conclusionThe natural compound-loaded SF nanoplatform prepared by SEDS indicates promising colon cancer-therapy potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.