ArticleScientific reports2017
Protein nutrition governs within-host race of honey bee pathogens.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-Analysis and Experimental Evidence Reveal No Impact of Nosema ceranae Infection on Honeybee Carbohydrate Consumption.Microbial ecology · 2025Pooled it
- Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence.Parasitology · 2024Pooled it
- Diet impacts the effects of thermal stress on infection outcomes.BMC ecology and evolution · 2026Article
- Effects of sugar type and regional variation on the biochemical composition of royal jelly (Apis mellifera L.).Scientific reports · 2025Article
- Article
- Field Application of an Innovative Approach to Assess Honeybee Health and Nutritional Status.Animals : an open access journal from MDPI · 2024Article
- Monitoring Immune Modulation in Season Population: Identifying Effects and Markers Related toBiomolecules · 2023Article
- Review
- Symptomatic Infection withAnimals : an open access journal from MDPI · 2023Article
- Geographical and Seasonal Analysis of the Honeybee Microbiome.Microbial ecology · 2023Article
- Decoupling the effects of nutrition, age, and behavioral caste on honey bee physiology, immunity, and colony health.Frontiers in physiology · 2023Article
- Dietary Supplement of Grape Wastes Enhances Honeybee Immune System and Reduces Deformed Wing Virus (DWV) Load.Antioxidants (Basel, Switzerland) · 2022Article
- Epidemiology of a major honey bee pathogen, deformed wing virus: potential worldwide replacement of genotype A by genotype B.International journal for parasitology. Parasites and wildlife · 2022Article
- Effects of different artificial diets on commercial honey bee colony performance, health biomarkers, and gut microbiota.BMC veterinary research · 2022Article
- Nosema apis and N. ceranae Infection in Honey bees: A Model for Host-Pathogen Interactions in Insects.Experientia supplementum (2012) · 2022Article
- Article
- Artificial Diets Modulate Infection Rates byMicroorganisms · 2021Article
- Can supplementary pollen feeding reduce varroa mite and virus levels and improve honey bee colony survival?Experimental & applied acarology · 2020Article
- From antagonism to synergism: Extreme differences in stressor interactions in one species.Scientific reports · 2020Article
- Macronutrients modulate survival to infection and immunity in Drosophila.The Journal of animal ecology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple infections are common in honey bees, Apis mellifera, but the possible role of nutrition in this regard is poorly understood. Microsporidian infections, which are promoted by protein-fed, can negatively correlate with virus infections, but the role of protein nutrition for the microsporidian-virus interface is unknown. Here, we challenged naturally deformed wing virus - B (DWV-B) infected adult honey bee workers fed with or without pollen ( = protein) in hoarding cages, with the microsporidian Nosema ceranae. Bee mortality was recorded for 14 days and N. ceranae spore loads and DWV-B titers were quantified. Amongst the groups inoculated with N. ceranae, more spores were counted in protein-fed bees. However, N. ceranae infected bees without protein-diet had reduced longevity compared to all other groups. N. ceranae infection had no effect on protein-fed bee's longevity, whereas bees supplied only with sugar-water showed reduced survival. Our data also support that protein-feeding can have a significant negative impact on virus infections in insects. The negative correlation between N. ceranae spore loads and DWV-B titers was stronger expressed in protein-fed hosts. Proteins not only enhance survival of infected hosts, but also significantly shape the microsporidian-virus interface, probably due to increased spore production and enhanced host immunity.
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