ArticleNature communications2017
Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 58 citations in OpenAlex.
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- Genomic insights into the diversity, antimicrobial resistance and zoonotic potential ofMicrobial genomics · 2025Article
- Understanding bovine genital campylobacteriosis: A comprehensive review of its threat to global cattle reproduction.Open veterinary journal · 2025Review
- Comparative pangenomic analysis of Campylobacter fetus isolated from Spanish bulls and other mammalian species.Scientific reports · 2024Article
- Analysis of twelve genomes of the bacteriumPeerJ · 2024Article
- Whole-genome comparison using complete genomes fromFrontiers in microbiology · 2024Article
- Campylobacter in Africa - A specific viewpoint.European journal of microbiology & immunology · 2023Review
- The History of Bovine Genital Campylobacteriosis in the Face of Political Turmoil and Structural Change in Cattle Farming in Germany.Veterinary sciences · 2023Review
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- Antimicrobial resistance inMicrobial genomics · 2023Article
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- Comparative genomic analysis ofFrontiers in microbiology · 2023Article
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- Genomic epidemiology ofFrontiers in veterinary science · 2022Article
- Protocol for post-processing of bacterial pangenome data using Pagoo pipeline.STAR protocols · 2021Article
- Complete Genome Sequence of Campylobacter fetus subsp.Microbiology resource announcements · 2021Article
- An object-oriented framework for evolutionary pangenome analysis.Cell reports methods · 2021Article
- Phylogenomic analysis forVeterinary world · 2021Article
- Accurate and fast identification ofVeterinary and animal science · 2021Article
- Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
28 authors at 16 institutions in 13 countries.
Funding
Abstract
Campylobacter fetus is a venereal pathogen of cattle and sheep, and an opportunistic human pathogen. It is often assumed that C. fetus infection occurs in humans as a zoonosis through food chain transmission. Here we show that mammalian C. fetus consists of distinct evolutionary lineages, primarily associated with either human or bovine hosts. We use whole-genome phylogenetics on 182 strains from 17 countries to provide evidence that C. fetus may have originated in humans around 10,500 years ago and may have "jumped" into cattle during the livestock domestication period. We detect C. fetus genomes in 8% of healthy human fecal metagenomes, where the human-associated lineages are the dominant type (78%). Thus, our work suggests that C. fetus is an unappreciated human intestinal pathobiont likely spread by human to human transmission. This genome-based evolutionary framework will facilitate C. fetus epidemiology research and the development of improved molecular diagnostics and prevention schemes for this neglected pathogen.
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