Evidence map›Paper›PMID 29118239›Full record

ArticleBiology letters2017

A positive genetic correlation between hypoxia tolerance and heat tolerance supports a controversial theory of heat stress.

Collin Teague, Jacob P Youngblood, Kinley Ragan, Michael J Angilletta, John M VandenBrooks

Abstract read
In one paragraph

Article in Biology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Collin TeagueSchool of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.
Jacob P YoungbloodSchool of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.ORCID http://orcid.org/0000-0003-3852-5008
Kinley RaganSchool of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.
Michael J AngillettaSchool of Life Sciences, Arizona State University, Tempe, AZ 85287, USA ma@asu.edu.ORCID http://orcid.org/0000-0002-3181-8361
John M VandenBrooksDepartment of Physiology, Midwestern University, Glendale, AZ 85308, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used quantitative genetics to test a controversial theory of heat stress, in which animals overheat when the demand for oxygen exceeds the supply. This theory, referred to as oxygen- and capacity-limited thermal tolerance, predicts a positive genetic correlation between hypoxia tolerance and heat tolerance. We demonstrate the first genetic correlation of this kind in a model organism,

Indexed as

AnaerobiosisAnimalsDrosophila melanogasterFemaleFlight, AnimalHot TemperatureOxygenStress, PhysiologicalThermotoleranceOxygenDrosophilahypoxiaoxygenperformancetemperaturetolerance

Identifiers

PMID29118239
PMCPMC5719369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.