ArticleProceedings. Biological sciences2017
Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming.
Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
- Divergent Thermal Reaction Norms of the Spontaneous Mutation Rate Among Populations of Chironomus riparius.Molecular ecology · 2026Article
- Suppressor analysis inFrontiers in microbiology · 2026Article
- Lifespan-extending downregulation of insulin signalling reduces germline mutation load.bioRxiv : the preprint server for biology · 2025Article
- Effects of Extreme Climatic Events on Evolutionary Processes.Global change biology · 2025Review
- The reliability of environmental cues shape learning and selection against deleterious alleles in seed beetles.Proceedings. Biological sciences · 2025Article
- Social context prevents heat hormetic effects against mutagens during fish development.FEBS letters · 2025Article
- Coevolution of longevity and female germline maintenance.Proceedings. Biological sciences · 2024Article
- Heat stress reveals a fertility debt owing to postcopulatory sexual selection.Evolution letters · 2024Article
- Effects of population density and environmental conditions on life-history prevalence in a migratory fish.Ecology and evolution · 2023Article
- Fasting increases investment in soma upon refeeding at the cost of gamete quality in zebrafish.Proceedings. Biological sciences · 2023Article
- Increased male investment in sperm competition results in reduced maintenance of gametes.PLoS biology · 2023Article
- Multigenerational downregulation of insulin/IGF-1 signaling in adulthood improves lineage survival, reproduction, and fitness in Caenorhabditis elegans supporting the developmental theory of ageing.Evolution; international journal of organic evolution · 2022Article
- Effects of developmental and adult environments on ageing.Evolution; international journal of organic evolution · 2022Article
- Towards a unified framework to study causality in Earth-life systems.Molecular ecology · 2021Article
- Temperature affects the repeatability of evolution in the microbial eukaryoteEcology and evolution · 2021Article
- Temperature dependence of spontaneous mutation rates.Genome research · 2021Article
- Inbreeding reduces fitness of seed beetles under thermal stress.Journal of evolutionary biology · 2021Article
- Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity.BMC biology · 2021Article
- Elevated temperature increases genome-wide selection on de novo mutations.Proceedings. Biological sciences · 2021Article
- Effector Avr4 inFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutation has a fundamental influence over evolutionary processes, but how evolutionary processes shape mutation rate remains less clear. In asexual unicellular organism, increased mutation rates have been observed in stressful environments and the reigning paradigm ascribes this increase to selection for evolvability. However, this explanation does not apply in sexually reproducing species, where little is known about how the environment affects mutation rate. Here we challenged experimental lines of seed beetle, evolved at ancestral temperature or under simulated climate warming, to repair induced mutations at ancestral and stressful temperature. Results show that temperature stress causes individuals to pass on a greater mutation load to their grand-offspring. This suggests that stress-induced mutation rates, in unicellular and multicellular organisms alike, can result from compromised germline DNA repair in low condition individuals. Moreover, lines adapted to simulated climate warming had evolved increased longevity at the cost of reproduction, and this allocation decision improved germline repair. These results suggest that mutation rates can be modulated by resource allocation trade-offs encompassing life-history traits and the germline and have important implications for rates of adaptation and extinction as well as our understanding of genetic diversity in multicellular organisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.