Evidence map›Paper›PMID 29117457›Full record

ArticleJournal of neuroendocrinology2017

Diurnal and photoperiodic changes in thyrotrophin-stimulating hormone β expression and associated regulation of deiodinase enzymes (DIO2, DIO3) in the female juvenile chicken hypothalamus.

I C Dunn, P W Wilson, Y Shi, D W Burt, A S I Loudon, P J Sharp

Open access · hybridAbstract read
In one paragraph

Article in Journal of neuroendocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Expression analysis ofArchives animal breeding · 2020
    Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

I C DunnRoslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, Scotland, UK.ORCID 0000-0003-3630-0120
P W WilsonRoslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, Scotland, UK.
Y ShiRoslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, Scotland, UK.
D W BurtUQ Genomics Initiative, University of Queensland, Saint Lucia, Qld, Australia.
A S I LoudonFaculty of Life Sciences, University of Manchester, Manchester, UK.
P J SharpRoslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, Scotland, UK.
Roslin Institute · GBThe University of Queensland · AUUniversity of Manchester · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G003033/1Biotechnology and Biological Sciences Research Council BBS/E/D/05191132Biotechnology and Biological Sciences Research Council BBS/E/D/20320000
6 · The paper itself

Abstract

Increased thyrotrophin-stimulating hormone β (TSHβ) expression in the pars tuberalis is assumed to be an early step in the neuroendocrine mechanism transducing photoperiodic information. The present study aimed to determine the relationship between long-photoperiod (LP) and diurnal TSHβ gene expression in the juvenile chicken by comparing LP-photostimulated birds with groups kept on a short photoperiod (SP) for 1 or 12 days. TSHβ expression increased by 3- and 23-fold after 1 and 12 days of LP-photostimulation both during the day and at night. Under both SP and LP conditions, TSHβ expression was between 3- and 14-fold higher at night than in the day, suggesting that TSHβ expression cycles in a diurnal pattern irrespective of photoperiod. The ratio of DIO2/3 was decreased on LPs, consequent to changes in DIO3 expression, although there was no evidence of any diurnal effect on DIO2 or DIO3 expression. Plasma prolactin concentrations revealed both an effect of LPs and time-of-day. Thus, TSHβ expression changes in a dynamic fashion both diurnally and in response to photoperiod.

Indexed as

Circadian RhythmPhotoperiodAnimalsAvian ProteinsBody WeightChickensFemaleGene ExpressionHypothalamusIodide PeroxidaseIodothyronine Deiodinase Type IILuteinizing HormoneOrgan SizeProlactinThyrotropin, beta SubunitAvian ProteinsIodide PeroxidaseIodothyronine Deiodinase Type IIiodothyronine deiodinase type IIILuteinizing HormoneProlactinThyrotropin, beta Subunitpars tuberalisphotoperiodismreproductionthyroid

Identifiers

PMID29117457
PMCPMC5767736
OpenAlexW2768044612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.