SynthesisDiabetic medicine : a journal of the British Diabetic Association2018
Intrapartum glycaemic control and neonatal hypoglycaemia in pregnancies complicated by diabetes: a systematic review.
Synthesis in Diabetic medicine : a journal of the British Diabetic Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management of Intrapartum Glycemia in Gestational Diabetic Mothers: A Randomized Controlled Trial
Intrapartum Maternal Glucose Control and Effect on Neonatal Hypoglycemia
Pilot Study of Intrapartum Insulin Pump Use: Feasibility, Efficacy and Safety
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Intrapartum maternal glycaemic control for the prevention of neonatal hypoglycaemia: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- A Systematic Review to Compare Adverse Pregnancy Outcomes in Women with Pregestational Diabetes and Gestational Diabetes.International journal of environmental research and public health · 2022Pooled it
- Lifestyle intervention during pregnancy in patients with gestational diabetes mellitus and the risk of neonatal hypoglycemia: A systematic review and meta-analysis.Frontiers in nutrition · 2022Pooled it
- Intrapartum and Early Postpartum Use of Automated Insulin Delivery in Type 1 Diabetes: A Prespecified Analysis of the CIRCUIT Randomized Controlled Trial.Diabetes care · 2026Trial
- Adaptability of Closed Loop During Labor, Delivery, and Postpartum: A Secondary Analysis of Data from Two Randomized Crossover Trials in Type 1 Diabetes Pregnancy.Diabetes technology & therapeutics · 2018Trial
- Streamlining intrapartum glycemic control: Subcutaneous insulin for intrapartum diabetes management.Pregnancy (Hoboken, N.J.) · 2026Article
- Intrapartum glucose metrics associated with adverse neonatal outcomes among people with gestational diabetes mellitus.Pregnancy (Hoboken, N.J.) · 2026Article
- Relationship between continuous maternal intrapartum and postpartum glucose monitoring metrics and neonatal outcomes and postpartum glucose metabolism in individuals with gestational diabetes.BMC pregnancy and childbirth · 2026Observational
- Practical Approach to Continuous Glucose Monitoring Interpretation and Automated Insulin Delivery Use in Pregnancy: Considerations for Obstetric Providers.Journal of diabetes science and technology · 2026Article
- Glycaemic control in labour with diabetes: GILD, a scoping study.Health technology assessment (Winchester, England) · 2025Article
- Diabetes Mellitus in Pregnancy: Implications for Obstetric Anesthesia.Anesthesiology · 2025Review
- Pregestational Diabetes and Adverse Pregnancy Results: A Mendelian Randomization Study.Archives of Iranian medicine · 2025Article
- Intrapartum Glycemic Control and Clinical Outcomes.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Glycemic control before delivery using continuous glucose monitoring and neonatal outcomes.American journal of obstetrics & gynecology MFM · 2024Article
- An automated insulin delivery system from pregestational care to postpartum in women with type 1 diabetes. Preliminary experience with telemedicine in 6 patients.Acta diabetologica · 2024Article
- Management of type 2 diabetes in pregnancy: a narrative review.Frontiers in endocrinology · 2023Review
- The association between maternal diabetes and neonatal seizures: a nested case-Control study.Frontiers in pediatrics · 2023Article
- Intrapartum and early postpartum glycemic profiles in women with gestational diabetes mellitus: an observational study.Chinese medical journal · 2022Observational
- Glycosylated hemoglobin A1c prior to delivery and neonatal hypoglycemia in pregnancies complicated by diabetes.American journal of obstetrics & gynecology MFM · 2022Article
- Reexamining intrapartum glucose control in patients with diabetes and risk of neonatal hypoglycemia.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo examine whether, in neonates of mothers with Type 1, Type 2 and gestational diabetes, in-target intrapartum glycaemic control was associated with a lower risk of neonatal hypoglycaemia compared with out-of-target glycaemic control.
methodsWe searched PubMed and EMBASE for all available publications, regardless of year, based on a published protocol (PROSPERO CRD42016052439). Studies were excluded if they did not report original data or were animal studies. Data were extracted from published reports in duplicate using a prespecified data extraction form. The main outcome of interest was the association between in-target intrapartum glycaemic control and neonatal hypoglycaemia.
resultsWe screened 2846 records for potential study inclusion; 23 studies, including approximately 2835 women with diabetes, were included in the systematic review. Only two of those studies specifically examined in-target vs out-of-target intrapartum glycaemic control. Of the studies included, six showed a relationship between intrapartum glucose and neonatal hypoglycaemia, five others showed a relationship in at least one of the analyses performed and 12 did not find a significant relationship. Only one study was identified as having a low risk of bias.
conclusionsThere is a paucity of high-quality data supporting the association of glucose during labour and delivery with neonatal hypoglycaemia in pregnancies complicated by diabetes. Further studies are required to examine the impact of tight glycaemic targets in labour.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.