ArticlePloS one2017
Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- Replacing Antibiotics with Synergistic Probiotics-Microalgae Consortium in Mud Crab (Antibiotics (Basel, Switzerland) · 2026Article
- IL-26 from innate lymphoid cells regulates early-life gut epithelial homeostasis by shaping microbiota composition.The EMBO journal · 2025Article
- Digestibility and Nutritional Value of MicroalgaAnimals : an open access journal from MDPI · 2025Article
- Targeting the plasticity of intestinal neutrophils: bidirectional regulation strategies by natural products.Frontiers in immunology · 2025Review
- Comparison of Different Microalgae Biomass Typologies Used in Rotifers Enrichment for Zebrafish (Aquaculture nutrition · 2025Article
- Green synthesis of chlorella-derived carbon dots and their fluorescence imaging in zebrafish.RSC advances · 2024Article
- Omics and imaging combinatorial approach reveals butyrate-induced inflammatory effects in the zebrafish gut.Animal microbiome · 2023Article
- Evaluation of the Combined Administration ofAnimals : an open access journal from MDPI · 2023Article
- Dietary Supplementation with a Blend of Hydrolyzable and Condensed Tannins Ameliorates Diet-Induced Intestinal Inflammation in Zebrafish (Animals : an open access journal from MDPI · 2022Article
- Impacts of Fortifying Nile Tilapia (Antioxidants (Basel, Switzerland) · 2022Article
- Dietary Lactoferrin Supplementation Improves Growth Performance and Intestinal Health of Juvenile Orange-Spotted Groupers (Metabolites · 2022Article
- Article
- Alternative Proteins for Fish Diets: Implications beyond Growth.Animals : an open access journal from MDPI · 2022Review
- Dietary supplementation with microalgae enhances the zebrafish growth performance by modulating immune status and gut microbiota.Applied microbiology and biotechnology · 2022Article
- High replacement of fishmeal byFrontiers in microbiology · 2022Article
- Dietary Inclusion of Seabuckthorn (Frontiers in physiology · 2022Article
- Improving the feasibility of aquaculture feed by using microalgae.Environmental science and pollution research international · 2021Review
- Article
- Sinomenine Hydrochloride Ameliorates Fish Foodborne EnteritisFrontiers in immunology · 2021Article
- Investigating Both Mucosal Immunity and Microbiota in Response to Gut Enteritis in Yellowtail Kingfish.Microorganisms · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soybean meal has been used in many commercial diets for farm fish; despite this component inducing intestinal inflammation. On the other hand, microalgae have increasingly been used as dietary supplements in fish feed. Nevertheless, the vast quantity of microalgae species means that many remain under- or unstudied, thus limiting wide scale commercial application. In this work, we evaluated the effects to zebrafish (Danio rerio) of including Tetraselmis sp (Ts); Phaeodactylum tricornutum (Pt); Chlorella sp (Ch); Nannochloropsis oculata (No); or Nannochloropsis gaditana (Ng) as additives in a soybean meal-based diet on intestinal inflammation and survival after Edwardsiella tarda infection. In larvae fed a soybean meal diet supplemented with Ts, Pt, Ch, or Ng, the quantity of neutrophils present in the intestine drastically decreased as compared to larvae fed only the soybean meal diet. Likewise, Ts or Ch supplements in soybean meal or fishmeal increased zebrafish survival by more than 20% after being challenged. In the case of Ts, the observed effect correlated with an increased number of neutrophils present at the infection site. These results suggest that the inclusion of Ts or Ch in fish diets could allow the use of SBM and at the same time improve performance against pathogen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.