Evidence map›Paper›PMID 29117112›Full record

ReviewInternational journal of molecular sciences2017

In Vivo Imaging of Microglial Calcium Signaling in Brain Inflammation and Injury.

Petr Tvrdik, M Yashar S Kalani

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Calcium Signalling in Microglia.Advances in neurobiology · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. L-Type CaInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Changing Functional Signatures of Microglia along the Axis of Brain Aging.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Petr TvrdikDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. petr.tvrdik@hsc.utah.edu.
M Yashar S KalaniDepartment of Neurosurgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. kalani@virginia.edu.
University of Utah · USUniversity of Virginia · US

Funding

Cre, Dre Dual Lineage Model for Calcium Imaging and Optogenetic ManipulationsR21OD016562 · OD · UNIVERSITY OF UTAH · PI TVRDIK, PETR · 2013 to 2014
$391k
NIH HHS R21 OD016562
6 · The paper itself

Abstract

Microglia, the innate immune sentinels of the central nervous system, are the most dynamic cells in the brain parenchyma. They are the first responders to insult and mediate neuroinflammation. Following cellular damage, microglia extend their processes towards the lesion, modify their morphology, release cytokines and other mediators, and eventually migrate towards the damaged area and remove cellular debris by phagocytosis. Intracellular Ca

Indexed as

Calcium SignalingAnimalsBrain InjuriesEncephalitisHumansIntravital MicroscopyMiceMicrogliaSignal TransductionAlzheimer’s diseasecalcium signalingGECIinflammationin vivo imagingischemic strokemicrogliaPC::G5-tdTtwo-photon

Identifiers

PMID29117112
PMCPMC5713335
OpenAlexW2767483601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.