ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018
Turn down for what? Patient outcomes associated with declining increased infectious risk kidneys.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Direct-Acting Antivirals in Kidney Transplantation From HCV-Viremic Donors to Negative Recipients: A Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Utilization of organs following implementation of the 2020 United States Public Health Service guideline recommendations.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Quantifying Center-level Aggressiveness in Transplanting Suboptimal, Deceased Donor Kidneys in the United States.Transplantation direct · 2026Article
- Trends in Increased Infection Risk Deceased Organ Donors. A Two-Centre Retrospective Study.Canadian journal of kidney health and disease · 2026Article
- Sexual and Gender Minorities in Organ and Tissue Donation and Transplantation (OTDT): A Survey of Canadian OTDT Health Care Workers.Canadian journal of kidney health and disease · 2026Article
- Sexual and gender minoritized persons in organ and tissue donation: a qualitative analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- Organ and tissue donation and sexual and gender minoritized persons: time for positive change.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- Increased Infectious Risk Donor Status and Equity-Relevant Predictors of Organ Donation Organization Approach and Caregiver Consent for Deceased Organ Donation in a Canadian Province (2015-2021).Clinical transplantation · 2024Observational
- A modular simulation framework for organ allocation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Article
- A modified Kidney Donor Risk Index for pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2023Article
- Effectiveness of education and attitudes toward different types of deceased donor kidneys: Survey analysis of single-center experience.Frontiers in public health · 2023Article
- Observational Study Examining Kidney Transplantation Outcomes Following Donation From Individuals That Died of Drug Toxicity in British Columbia, Canada.Canadian journal of kidney health and disease · 2023Article
- Utilization of HCV viremic donors in kidney transplantation: a chance or a threat?Renal failure · 2022Review
- Kidney Transplantation From Deceased Donors With Bloodstream Infection: A Multicenter Retrospective Study.Journal of Korean medical science · 2022Article
- Deceased Donor Characteristics and Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022Review
- The 3-T Model of Informed Consent for Nonstandard Risk Donors: A Proposal for Transplant Clinical Practice.Transplantation direct · 2021Article
- Successful Implementation of an Increased Viral Risk Donor Waiting List for Preconsented Kidney Transplant Candidates in Victoria, Australia.Transplantation direct · 2021Article
- Identifying Needs and Barriers to Engage Family Members in Transplant Candidate Care.Progress in transplantation (Aliso Viejo, Calif.) · 2021Article
- Pretransplant Hepatitis C Virus Treatment Decreases Access to High-quality Livers.Transplantation direct · 2021Article
- Donor management using a specialized donor care facility is associated with higher organ utilization from drug overdose donors.Clinical transplantation · 2021Article
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Authors and funding
8 authors.
Funding
Abstract
Transplant candidates who accept a kidney labeled increased risk for disease transmission (IRD) accept a low risk of window period infection, yet those who decline must wait for another offer that might harbor other risks or never even come. To characterize survival benefit of accepting IRD kidneys, we used 2010-2014 Scientific Registry of Transplant Recipients data to identify 104 998 adult transplant candidates who were offered IRD kidneys that were eventually accepted by someone; the median (interquartile range) Kidney Donor Profile Index (KDPI) of these kidneys was 30 (16-49). We followed patients from the offer decision until death or end-of-study. After 5 years, only 31.0% of candidates who declined IRDs later received non-IRD deceased donor kidney transplants; the median KDPI of these non-IRD kidneys was 52, compared to 21 of the IRDs they had declined. After a brief risk period in the first 30 days following IRD acceptance (adjusted hazard ratio [aHR] accept vs decline:
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