Evidence map›Paper›PMID 29116591›Full record

ArticleVirologica Sinica2017

Prevalence of Kaposi's sarcoma-associated herpesvirus in Uygur and Han populations from the Urumqi and Kashgar regions of Xinjiang, China.

Jun Zheng, Yang Yang, Meng Cui, Zhan-Jun Shu, Li-Li Han, Zhen-Qiu Liu, Charles Wood, Tiejun Zhang, Yan Zeng

Open access · hybridAbstract read
In one paragraph

Article in Virologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cellular microRNA-127-3p suppresses oncogenic herpesvirus-induced transformation and tumorigenesis via down-regulation of SKP2.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Article
  5. Article
  6. Kaposi's sarcoma herpesvirus is associated with osteosarcoma in Xinjiang populations.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Review
  8. Article
  9. Prevalence of Kaposi's sarcoma-associated herpesvirus and transfusion-transmissible infections in Tanzanian blood donors.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jun ZhengKey Laboratory of Xinjiang Endemic and Ethnic Disease & Department of Biochemistry, School of Medicine, Shihezi University, Shihezi, 832000, China.
Yang YangKey Laboratory of Xinjiang Endemic and Ethnic Disease & Department of Biochemistry, School of Medicine, Shihezi University, Shihezi, 832000, China.
Meng CuiKey Laboratory of Xinjiang Endemic and Ethnic Disease & Department of Biochemistry, School of Medicine, Shihezi University, Shihezi, 832000, China.
Zhan-Jun ShuDivision of AIDS Research, National Traditional Chinese Medicine Clinical Research Bases in Xinjiang, Urumqi, 830000, China.
Li-Li HanDepartment of Gynecology, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, 830001, China.
Zhen-Qiu LiuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200032, China.
Charles WoodNebraska Center of Virology and the School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, 68583, USA.
Tiejun ZhangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, 200032, China. tjzhang@shmu.edu.cn.ORCID http://orcid.org/0000-0002-5187-7393
Yan ZengKey Laboratory of Xinjiang Endemic and Ethnic Disease & Department of Biochemistry, School of Medicine, Shihezi University, Shihezi, 832000, China. yzeng910@163.com.ORCID http://orcid.org/0000-0002-2396-2830
Shihezi University · CNFudan University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNUniversity of Nebraska–Lincoln · USXinjiang Medical University · CN

Funding

VIRAL SHUTOFF OF HOST TRANSCRIPTION--PBCV-1 INFECTEDP20RR015635 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2000 to 2009
$22.1M
KAPOSIS SARCOMA AND HUMAN HERPESVIRUS IN AFRICAR01CA075903 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 1998 to 2015
$11.1M
NCI NIH HHS R01 CA075903NCRR NIH HHS P20 RR015635
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious etiologic agent associated with Kaposi's sarcoma (KS), primary effusion lymphoma, and multicentric Castleman disease. It has been shown that high KSHV prevalence and high incidence of both classic KS and AIDSassociated KS are found mostly among people of Uygur ethnicity in Xinjiang, while people of Han ethnicity in Xinjiang have a higher KSHV seroprevalence than those of other Han populations in mainland China. However, it is still unclear why there is such geographical and population variation in KSHV distribution in China. In this work, we focused on the populations in the Kashgar region and Urumqi area, where a total of 1294 research subjects were randomly selected to investigate the potential correlation between KSHV prevalence and different ethnicities in endemic areas of Xinjiang, and to determine risk factors that may affect KSHV infection rates or KS incidence. We identified a high seroprevalence of KSHV and high peripheral blood DNA infection in the general Uygur and Han populations in both Urumqi and Kashgar regions of Xinjiang, and determined that advancing age, low education level, and stationary population status affect KSHV infection rates. Further, KSHV-positive Uygur participants were shown to have higher prevalence of neutralizing antibodies and neutralizing antibody titers than KSHV-positive Han participants.

Indexed as

AdultChinaDNA, ViralFemaleHerpesviridae InfectionsHerpesvirus 8, HumanHumansIncidenceMaleMiddle AgedPrevalenceSarcoma, KaposiSeroepidemiologic StudiesYoung AdultDNA, ViralHan ethnicityKaposi’s sarcoma associated herpesvirus (KSHV)prevalenceUygur ethnicityXinjiang

Identifiers

PMID29116591
PMCPMC6704202
OpenAlexW2768033552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.