Evidence map›Paper›PMID 29116574›Full record

ArticleJournal of echocardiography2018

Successful percutaneous coronary intervention significantly improves coronary sinus blood flow as assessed by transthoracic echocardiography.

Radmila Lyubarova, William E Boden, Steven A Fein, Joshua Schulman-Marcus, Mikhail Torosoff

Abstract read
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In one paragraph

Article in Journal of echocardiography, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Radmila LyubarovaDivision of Cardiology, Albany Medical College, 47 New Scotland Avenue, MC44, Albany, NY, 12208, USA. LyubarR@mail.amc.edu.ORCID 0000-0001-9163-7602
William E BodenClinical Trials Network, VA New England Healthcare System, Boston University School of Medicine, Boston, MA, USA.
Steven A FeinDivision of Cardiology, Albany Medical College, 47 New Scotland Avenue, MC44, Albany, NY, 12208, USA.
Joshua Schulman-MarcusDivision of Cardiology, Albany Medical College, 47 New Scotland Avenue, MC44, Albany, NY, 12208, USA.
Mikhail TorosoffDivision of Cardiology, Albany Medical College, 47 New Scotland Avenue, MC44, Albany, NY, 12208, USA.
Albany Medical Center Hospital · USBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransthoracic echocardiography (TTE) has been used to assess coronary sinus blood flow (CSBF), which reflects total coronary arterial blood flow. Successful angioplasty is expected to improve coronary arterial blood flow. Changes in CSBF after percutaneous coronary intervention (PCI), as assessed by TTE, have not been systematically evaluated. HYPOTHESIS: TTE can be utilized to reflect increased CSBF after a successful, clinically indicated PCI.

methodsThe study cohort included 31 patients (18 females, 62 ± 11 years old) referred for diagnostic cardiac catheterization for suspected coronary artery disease and possible PCI, when clinically indicated. All performed PCIs were successful, with good angiographic outcome. CSBF per cardiac cycle (mL/beat) was measured using transthoracic two-dimensional and Doppler flow imaging as the product of coronary sinus (CS) area and CS flow time-velocity integral. CSBF per minute (mL/min) was calculated as the product of heart rate and CSBF per cardiac cycle. In each patient, CSBF was assessed prospectively, before and after cardiac catheterization with and without clinically indicated PCI. Within- and between-group differences in CSBF before and after PCI were assessed using repeated measures analysis of variance.

resultsTechnically adequate CSBF measurements were obtained in 24 patients (77%). In patients who did not undergo PCI, there was no significant change in CSBF (278.1 ± 344.1 versus 342.7 ± 248.5, p = 0.36). By contrast, among patients who underwent PCI, CSBF increased significantly (254.3 ± 194.7 versus 618.3 ± 358.5 mL/min, p < 0.01, p-interaction = 0.03). Other hemodynamic and echocardiographic parameters did not change significantly before and after cardiac catheterization in either treatment group.

conclusionsTransthoracic echocardiographic assessment can be employed to document CSBF changes after angioplasty. Future studies are needed to explore the clinical utility of this noninvasive metric.

Indexed as

Percutaneous Coronary InterventionAgedBlood Flow VelocityCohort StudiesCoronary Artery DiseaseCoronary SinusEchocardiographyEchocardiography, Doppler, ColorFemaleHumansMaleMiddle AgedTreatment OutcomeCoronary artery diseaseCoronary perfusionCoronary sinus blood flowPercutaneous coronary interventionTransthoracic echocardiography

Identifiers

PMID29116574
OpenAlexW2767839990

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.