ArticleAnnals of intensive care2017
Admission of tetanus patients to the ICU: a retrospective multicentre study.
Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- Human versus equine intramuscular antitoxin, with or without human intrathecal antitoxin, for the treatment of adults with tetanus: a 2 × 2 factorial randomised controlled trial.The Lancet. Global health · 2022Trial
- Clinical and epidemiological profile of patients with accidental tetanus in a referral hospital: a 13-year historical series.Infection · 2026Article
- Clinical characteristics, management, and outcomes of severe tetanus in the intensive care unit.BMC infectious diseases · 2026Observational
- Mortality and Associated Factors Among Adult Tetanus Patients Admitted at Public Hospitals in Bahir Dar City, Ethiopia: A Cross-Sectional Study.Health science reports · 2026Article
- Neonatal tetanus in undocumented migrant families in Saudi Arabia: outcomes and critical care resource utilization in a 10-year tertiary PICU cohort.Frontiers in pediatrics · 2026Article
- Tetanus: recognition and management.The Lancet. Infectious diseases · 2025Review
- Functional prognosis of older adults with tetanus in Japan: a single-center retrospective study.BMC infectious diseases · 2025Article
- Knowledge, attitudes, and practices regarding tetanus: a case of healthcare workers in the emergency and intensive care departments of a regional hospital in the northern region of Morocco.BMC health services research · 2025Article
- Global analysis of tetanus incidence and mortality in children under 5 years: findings from the Global Burden of Disease Study 2021.BMJ paediatrics open · 2025Article
- Difficult diagnosis of tetanus in a sedated patient after ileal resection.JA clinical reports · 2025Article
- Factors Influencing the Length of Emergency Intensive Care Unit Stay in Adult Tetanus Patients.International journal of general medicine · 2025Article
- Generalized tetanus complicated with Takotsubo-cardiomyopathy in a septuagenarian following a laceration injury with soil contamination - a case report.International journal of emergency medicine · 2024Article
- Tetanus Severity Classification in Low-Middle Income Countries through ECG Wearable Sensors and a 1D-Vision Transformer.BioMedInformatics · 2024Article
- Risk assessment of severe adult tetanus using the NLR and AST level and construction of a nomogram prediction model.Heliyon · 2024Article
- Tetanus Cases in Mogadishu-Somalia: A Tragic Disease Despite the Existence of a Century-Old Safe and Efficient Tetanus Vaccine.International journal of general medicine · 2024Article
- Adult patients with tetanus in Slovenia 2006-2021 : Results of a national cohort study.Wiener klinische Wochenschrift · 2023Article
- 2D-WinSpatt-Net: A Dual Spatial Self-Attention Vision Transformer Boosts Classification of Tetanus Severity for Patients Wearing ECG Sensors in Low- and Middle-Income Countries.Sensors (Basel, Switzerland) · 2023Article
- Generalized tetanus: a pediatric case report and literature review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2023Review
- 6084 Cases of Adult Tetanus from China: A Literature Analysis.Infection and drug resistance · 2023Article
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Authors and funding
24 authors at 17 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn extended course of tetanus (up to 6 weeks) requiring ICU admission and protracted mechanical ventilation (MV) may have a significant impact on short- and long-term survival. The subject is noteworthy and deserves to be discussed.
methodsTwenty-two ICUs in France performed tetanus screenings on patients admitted between January 2000 and December 2014. Retrospective data were collected from hospital databases and through the registers of the town hall of the patients.
resultsSeventy patients were included in 15 different ICUs. Sixty-three patients suffered from severe or very severe tetanus according to the Ablett classification. The median age was 80 years [interquartile range 73-84], and 86% of patients were women. Ninety per cent of patients (n = 63) required MV for a median of 36 days [26-46], and 66% required administration of a neuromuscular-blocking agent for 23 days [14-29]. A nosocomial infection occurred in 43 patients (61%). ICU and 1-year mortality rates were 14% (n = 10) and 16% (n = 11), respectively. Forty-five per cent of deaths occurred during the first week. Advanced age, a higher SAPS II, any infection, and the use of vasopressors were significantly associated with a lower number of days alive without ventilator support by day 90. Age was the only factor that significantly differed between deceased and survivors at 1 year (83 [81-85] vs. 79 [73-84] years, respectively; p = 0.03). Sixty-one per cent of survivors suffered no impairment to their functional status.
conclusionIn a high-income country, tetanus mainly occurs in healthy elderly women. Despite prolonged MV and extended ICU length of stay, we observed a low 1-year mortality rate and good long-term functional status.
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