Evidence map›Paper›PMID 29116551›Full record

ArticlePurinergic signalling2018

Anti-inflammatory effect of a novel locally acting A

L Antonioli, A El-Tayeb, C Pellegrini, M Fornai, O Awwad, G Giustarini, G Natale, L Ryskalin, Z H Németh, C E Müller and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Purinergic signalling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Inhibition of visceral adipose tissue-derived pathogenic signals by activation of adenosine AAmerican journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  5. Article
  6. Review
  7. Adenosine and Inflammation: Here, There and Everywhere.International journal of molecular sciences · 2021
    Review
  8. A Novel Role of AFrontiers in pharmacology · 2021
    Article
  9. Homocysteine concentration and adenosine AJournal of cellular and molecular medicine · 2020
    Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

L AntonioliDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.
A El-TayebPharmaCenter Bonn, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
C PellegriniDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.
M FornaiDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy. mfornai74@gmail.com.
O AwwadDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.
G GiustariniDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.
G NataleDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
L RyskalinDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Z H NémethDepartment of Surgery, Morristown Medical Center, Morristown, NJ, USA.
C E MüllerPharmaCenter Bonn, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
C BlandizziDepartment of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.
R ColucciDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
University of Pisa · ITUniversity of Bonn · DEMorristown Medical Center · USUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine represents a powerful modulating factor, which has been shown to orchestrate the scope, duration, and remission of the inflammatory response through the activation of four specific receptors, classified as A

Indexed as

Adenosine A2 Receptor AgonistsAdjuvants, ImmunologicAnimalsAnti-Inflammatory Agents, Non-SteroidalColitisColonDisease Models, AnimalFuransMaleOxazoloneRatsRats, Sprague-DawleyAdenosine A2 Receptor AgonistsAdjuvants, ImmunologicAnti-Inflammatory Agents, Non-SteroidalFuransOxazolonePSB-0777A2A adenosine receptorColitisColonInflammationLocally acting agent

Identifiers

PMID29116551
PMCPMC5842152
OpenAlexW2767631063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.