Evidence map›Paper›PMID 29116538›Full record

ArticleEnvironmental science and pollution research international2018

Environmentally benign nanometric neem-laced urea emulsion for controlling mosquito population in environment.

Prabhakar Mishra, Merlyn Keziah Samuel, Ruchishya Reddy, Brij Kishore Tyagi, Amitava Mukherjee, Natarajan Chandrasekaran

Abstract read
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Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Targeting the vector of arbovirusesBeilstein journal of nanotechnology · 2025
    Review
  2. Article
  3. Exploring the therapeutic potential of Neem (Annals of translational medicine · 2022
    Review
  4. Botanical insecticide-based nanosystems for the control of Aedes (Stegomyia) aegypti larvae.Environmental science and pollution research international · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prabhakar MishraCentre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
Merlyn Keziah SamuelCentre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
Ruchishya ReddyCentre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
Brij Kishore TyagiDepartment of Zoology & Environment Science, Punjabi University, Patiala, Punjab, India.
Amitava MukherjeeCentre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
Natarajan ChandrasekaranCentre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India. nchandrasekaran@vit.ac.in.

Funding

Indian Council of Medical Research ICMR VSF (VIR/RCI/AES/58/2014/ECD-1)
6 · The paper itself

Abstract

The increasing risk of vector-borne diseases and the environmental pollution in the day-to-day life due to the usage of the conventional pesticides makes the role of nanotechnology to come into the action. The current study deals with one of the applications of nanotechnology through the formulation of neem urea nanoemulsion (NUNE). NUNE was formulated using neem oil, Tween 20, and urea using the microfluidization method. Prior to the development of nanoemulsion, the ratio of oil/surfactant/urea was optimized using the response surface modeling method. The mean droplet size of the nanoemulsion was found to be 19.3 ± 1.34 nm. The nanoemulsion was found to be stable for the period of 4 days in the field conditions which aids to its mosquitocidal activity. The nanoemulsion exhibited a potent ovicidal and larvicidal activity against A. aegypti and C. tritaeniorhynchus vectors. This result was corroborated with the histopathological analysis of the NUNE-treated larvae. Further, the effect of NUNE on the biochemical profile of the target host was assessed and was found to be efficacious compared to the bulk counterpart. The nanoemulsion was then checked for its biosafety towards the non-target species like plant beneficial bacterium (E. ludwigii), and phytotoxicity was assessed towards the paddy plant (O. sativa). Nanometric emulsion at the concentration used for the mosquitocidal application was found to be potentially safe towards the environment. Therefore, the nanometric neem-laced urea emulsion tends to be an efficient mosquito control agent with an environmentally benign property.

Indexed as

NanoparticlesAedesAnimalsAzadirachtaCulexCulicidaeEmulsionsGlyceridesInsecticidesLarvaMosquito ControlMosquito VectorsPolysorbatesTerpenesUreaEmulsionsGlyceridesInsecticidesneem oilPolysorbatesTerpenesUreaAedes aegyptiCulex tritaeniorhynchusEnterobacter ludwigiiHigh-pressure homogenizationLarvicidalNeem urea nanoemulsionOryza sativaOvicidalResponse surface modeling

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.