ReviewCurrent psychiatry reports2017
Sex Differences in Trauma-Related Psychopathology: a Critical Review of Neuroimaging Literature (2014-2017).
Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neuroimaging Correlates of Post-Traumatic Stress Disorder in Traumatic Brain Injury: A Systematic Review of the Literature.Journal of neurotrauma · 2023Pooled it
- Network Centrality and Modularity of Structural Covariance Networks in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study.Brain connectivity · 2023Pooled it
- Neurobiological Alterations in Females With PTSD: A Systematic Review.Frontiers in psychiatry · 2022Pooled it
- Amygdala-related electroencephalogram neurofeedback as add-on therapy for treatment-resistant childhood sexual abuse posttraumatic stress disorder: feasibility study.Psychiatry and clinical neurosciences · 2024Trial
- Sex-stratified insights into the genetics of brain volumes in late adulthood.Biology of sex differences · 2026Article
- Alcohol misuse and negative emotion processing in neurotypical drinkers: Sex differences in behavioral and neural markers.Psychiatry research. Neuroimaging · 2026Article
- Sex differences in the association of adverse childhood experiences with brain and cognition along a continuum of risk for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Treatment stigma mediates relationships between morally injurious events and depression, PTSD and anxiety symptoms.European journal of psychotraumatology · 2025Article
- Associations between perceived excessive maternal control in childhood, well-being, and dorsal striatum volume in older adults.Scientific reports · 2025Article
- Using Functional Near-Infrared Spectroscopy to Elucidate Neurophysiological Mechanism of Action of Equine-Assisted Services: Proof-of-Concept Study.International journal of environmental research and public health · 2025Article
- Childhood Trauma andmedRxiv : the preprint server for health sciences · 2025Article
- Amygdala Structure and Function: Association With Transdiagnostic Trauma Severity in Anxiety and Mood Disorder Patients.Psychophysiology · 2025Article
- Exploring the impact of biological sex on intrinsic connectivity networks in PTSD: A data-driven approach.Progress in neuro-psychopharmacology & biological psychiatry · 2025Article
- Investigating the transition of psychopathological symptoms from childhood to adolescence in maltreated youth: a cross sectional study.Frontiers in psychiatry · 2025Article
- Neuroimaging in post-traumatic stress disorder: a narrative review.Archives of medical science : AMS · 2025Article
- Nanoparticle targeting strategies for traumatic brain injury.Journal of neural engineering · 2024Review
- Neuroimaging of posttraumatic stress disorder in adults and youth: progress over the last decade on three leading questions of the field.Molecular psychiatry · 2024Review
- Identifying cortical structure markers of resilience to adversity in young people using surface-based morphometry.Social cognitive and affective neuroscience · 2024Article
- Childhood stress, gender, and cognitive control: Midline theta power.Journal of psychiatric research · 2024Article
- Functional connectivity of amygdala subnuclei in PTSD: a narrative review.Molecular psychiatry · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purpose of reviewSex differences in the epidemiology and clinical presentation of trauma-related psychopathology have long been documented. Multiple underlying mechanisms have been examined, both psychosocial and biological. Among the most promising biological mechanisms are neural substrates of trauma-related psychopathology that have been uncovered in recent years. RECENT
findingsNeuroimaging studies of sex-related heterogeneity published over the past 3 years (2014-2017) demonstrate an interaction between sex and type, timing, and load of trauma exposure. These studies suggest that, for males, early trauma exposure may involve a loss of gray matter in the limbic system, including the prefrontal cortex (PFC), amygdala, and hippocampus, and an over-activity and increased connectivity of salience hubs, and particularly dorsal anterior cingulate cortex (dACC). For females, however, early trauma exposure may involve overactive and possibly an enlarged amygdala, as well as decreased connectivity of salience hubs such as the dACC. Underlying mechanisms may include interaction with several endocrine systems and result in differential neural response to naturally occurring and added endocrine ligands, as well as sex-specific genetic and epigenetic risk and resilience factors. This complex interaction between multiple biological systems may be associated with sex-specific behavioral patterns, in turn associated with trauma-related psychopathology. While substantial number of published studies present preliminary evidence for neural mechanisms of sex-specific posttraumatic responses, there is a paucity of research directly designed to examine sex as a biological factor in trauma-related psychopathology. Specific foci for future studies aiming to bridge current gaps in the literature are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.