ArticleInflammopharmacology2018
Potential usefulness of methyl gallate in the treatment of experimental colitis.
Article in Inflammopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- UPLC-HRMS-MS profiling of Ludwigia adscendens subsp. diffusa aerial parts and investigation of the anti-inflammatory effect.Scientific reports · 2025Article
- Antioxidant Therapy in Inflammatory Bowel Diseases: How Far Have We Come and How Close Are We?Antioxidants (Basel, Switzerland) · 2024Review
- Insights into molecular mechanisms of phytochemicals in quorum sensing modulation for bacterial biofilm control.Archives of microbiology · 2024Review
- Effects of Crude Extract ofAntioxidants (Basel, Switzerland) · 2024Article
- Effect of Methyl Gallate on 1-Nitropyrene-Induced Keratinocyte Toxicity in a Human and Canine Skin Model.Journal of microbiology and biotechnology · 2022Article
- Article
- In vitro antibacterial activity of Loxostylis alata extracts and isolated compounds against Salmonella species.BMC complementary medicine and therapies · 2021Article
- New Class of Anti-Inflammatory Therapeutics Based on Gold (III) Complexes in Intestinal Inflammation-Proof of Concept Based on In Vitro and In Vivo Studies.International journal of molecular sciences · 2021Article
- Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020Article
- Gallincin ameliorates colitis-associated inflammation and barrier function in mice based on network pharmacology prediction.The Journal of international medical research · 2020Article
- Bacterial ClpP Protease Is a Potential Target for Methyl Gallate.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Methyl gallate is a gallotannin widely distributed in nature. Previous studies have demonstrated its antioxidant, anti-inflammatory, antimicrobial and anti-tumor activities. In the present study, the activity of methyl gallate on experimental models of inflammatory bowel disease has been investigated. Experimental colitis was induced in Sprague-Dawley rats through the intracolonic instillation of an acetic acid solution (2 mL, 4% v/v). Methyl gallate (100 and 300 mg/kg, p.o.) and the reference drug mesalazine (100 mg/kg, p.o.) were tested. Methyl gallate induced a significant reduction in the colon weight/length ratio and macroscopic lesion score. Besides, the malondialdehyde content and the GSSG/GSH ratio were remarkably decreased. Furthermore, the administration of methyl gallate reduced the expression of COX
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Registered trials
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