ArticleInternational orthopaedics2018
Injectable, biomechanically robust, biodegradable and osseointegrative bone cement for percutaneous kyphoplasty and vertebroplasty.
Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
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Who cites it
13 citing papers in PubMed.
- Incidence and risk factors of poor prognosis in patients with OVCF following day surgery of percutaneous kyphoplasty: a retrospective study.BMC musculoskeletal disorders · 2025Article
- High Strength and Shape Memory Spinal Fusion Device for Minimally Invasive Interbody Fusions.International journal of nanomedicine · 2024Article
- Bioactive mineralized small intestinal submucosa acellular matrix/PMMA bone cement for vertebral bone regeneration.Regenerative biomaterials · 2023Article
- Sudoku of porous, injectable calcium phosphate cements - Path to osteoinductivity.Bioactive materials · 2022Review
- Biodegradable and Biocompatible Adhesives for the Effective Stabilisation, Repair and Regeneration of Bone.Bioengineering (Basel, Switzerland) · 2022Review
- Evaluation of the Effect of Selected Physiological Fluid Contaminants on the Mechanical Properties of Selected Medium-Viscosity PMMA Bone Cements.Materials (Basel, Switzerland) · 2022Article
- Cortical bone trajectory fixation in cemented vertebrae in lumbar degenerative disease: A case report.World journal of clinical cases · 2021Article
- Effect of Physiological Saline Solution Contamination on Selected Mechanical Properties of Seasoned Acrylic Bone Cements of Medium and High Viscosity.Materials (Basel, Switzerland) · 2020Article
- Modified kyphoplasty with controllable balloon dilatation for treatment of thoracolumbar osteoporotic vertebral compression fractures.International orthopaedics · 2020Article
- Bioactive poly (methyl methacrylate) bone cement for the treatment of osteoporotic vertebral compression fractures.Theranostics · 2020Article
- A novel calcium phosphate-based nanocomposite for the augmentation of cement-injectable cannulated pedicle screws fixation: A cadaver and biomechanical study.Journal of orthopaedic translation · 2020Article
- Effect of Physiological Fluids Contamination on Selected Mechanical Properties of Acrylate Bone Cement.Materials (Basel, Switzerland) · 2019Article
- Effect of surgical factors on the augmentation of cement-injectable cannulated pedicle screw fixation by a novel calcium phosphate-based nanocomposite.Frontiers of medicine · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposePoly(methyl methacrylate) (PMMA) cement is widely used for percutaneous kyphoplasty and vertebroplasty (PKP and PVP) but possesses formidable shortcomings due to non-degradability. Here, a biodegradable replacement is developed.
methodsCalcium phosphate cement (CPC) was redesigned by incorporating starch and BaSO
resultsCPB revealed appropriate injectability and setting ability for PKP and PVP. More importantly, its biomechanical strengths measured by in vitro and in vivo models were not less than that of PMMA, while its biodegradability and osseointegrative capacities were significantly enhanced compared to PMMA.
conclusionsCPB is injectable, biomechanically robust, biodegradable and osseointegrative, demonstrating revolutionary potential for the application in PKP and PVP.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.