SynthesisScientific reports2017
Cardiovascular consequences of myocardial bridging: A meta-analysis and meta-regression.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic impact of myocardial bridge on long-term mortality and morbidity: A meta-analysis and systematic review.The international journal of cardiovascular imaging · 2026Pooled it
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- Clinical features and prognosis in patients with coronary anomalies: the experiences and follow-up results of a single center.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Unveiling the Masquerading of Myocardial Bridging in Cardiovascular Diseases.Reviews in cardiovascular medicine · 2025Review
- Coronary Endothelial Dysfunction and Vasomotor Dysregulation in Myocardial Bridging.Journal of cardiovascular development and disease · 2025Review
- Ischemia with no obstructed coronary arteries and microvascular testing procedures: a review of utility, pharmacotherapy, and current challenges.Frontiers in cardiovascular medicine · 2025Review
- Efficacy and safety of drug-coated balloon angioplasty in proximal LAD stenosis with distal myocardial bridge: a 12-month comparative study with drug-eluting stents.Frontiers in cardiovascular medicine · 2025Article
- Unmasking Myocardial Bridging: Multimodal Imaging and Tailored Medical Approach in Exercise-induced Angina - A Case Report.Journal of the Saudi Heart Association · 2025Article
- Clinical Outcomes of Concomitant Coronary Artery Bypass Grafting During Ventricular Septal Myectomy.Journal of the American Heart Association · 2024Article
- Utility of the AngelMed Guardian System in myocardial bridging: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Article
- Myocardial ischemia caused by the synergistic effect of myocardial bridge and moderate stenosis: case report.BMC cardiovascular disorders · 2024Article
- Prognostic Implications of Resistive Reserve Ratio in Patients With Nonobstructive Coronary Artery Disease With Myocardial Bridging.Journal of the American Heart Association · 2024Article
- Concurrent Myocardial Bridging and Coronary Artery Disease: A Study of an Iranian Population.The journal of Tehran Heart Center · 2024Article
- Myocardial Bridging Increases the Risk of Adverse Cardiovascular Events in Patients without Coronary Atherosclerosis.Life (Basel, Switzerland) · 2024Article
- Beating the heart failure odds: long-term survival after myocardial ischemia in juvenile rainbow trout.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- High Prevalence of Myocardial Bridging Detected in an Indonesian Population Using Multi-Detector Computed Tomography.Medicina (Kaunas, Lithuania) · 2024Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial bridging, a congenital abnormality in which a coronary artery tunnels through the myocardial fibres was usually considered a benign condition. Many studies suggested a potential hemodynamic significance of myocardial bridging and some, usually case reports, implied a possible correlation between it and various cardiovascular pathologies like acute myocardial infarction, ventricular rupture, life-threatening arrhythmias, hypertrophic cardiomyopathy, apical ballooning syndrome or sudden death. The main objective of this article is to evaluate whether myocardial bridging may be associated with significant cardiac effects or if it is strictly a benign anatomical variation. To this purpose, we performed a meta-analysis (performed using the inverse variance heterogeneity model) and meta-regression, on scientific articles selected from three main databases (Scopus, Web of Science, Pubmed). The study included 21 articles. MB was associated with major adverse cardiac events - OR = 1.52 (1.01-2.30), and myocardial ischemia OR = 3.00 (1.02-8.82) but not with acute myocardial infarction, cardiovascular death, ischemia identified using imaging techniques, or positive exercise stress testing. Overall, myocardial bridging may have significant cardiovascular consequences (MACE, myocardial ischemia). More studies are needed to reveal/refute a clear association with MI, sudden death or other cardiovascular pathologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.