Evidence map›Paper›PMID 29116043›Full record

ArticleeLife2017

Two receptor tyrosine phosphatases dictate the depth of axonal stabilizing layer in the visual system.

Satoko Hakeda-Suzuki, Hiroki Takechi, Hinata Kawamura, Takashi Suzuki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Satoko Hakeda-SuzukiSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Hiroki TakechiSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Hinata KawamuraSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Takashi SuzukiSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.ORCID http://orcid.org/0000-0001-9093-2562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Formation of a functional neuronal network requires not only precise target recognition, but also stabilization of axonal contacts within their appropriate synaptic layers. Little is known about the molecular mechanisms underlying the stabilization of axonal connections after reaching their specifically targeted layers. Here, we show that two receptor protein tyrosine phosphatases (RPTPs), LAR and Ptp69D, act redundantly in photoreceptor afferents to stabilize axonal connections to the specific layers of the

Indexed as

AnimalsAxonsDrosophilaDrosophila ProteinsEmbryo, NonmammalianGene Knockout TechniquesGenetic Complementation TestPhotoreceptor CellsReceptor-Like Protein Tyrosine PhosphatasesDrosophila ProteinsLar protein, DrosophilaPTP69D protein, DrosophilaReceptor-Like Protein Tyrosine Phosphatasesaxon stabilizationcell-cell communicationdevelopmental biologyD. melanogasterdrosophila visual systemneurosciencereceptor tyrosine phosphatasesstem cellssynaptic layer specific targeting

Identifiers

PMID29116043
PMCPMC5683756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.