Trial reportHead & face medicine2017
The influence of dexamethasone on postoperative swelling and neurosensory disturbances after orthognathic surgery: a randomized controlled clinical trial.
Trial report in Head & face medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Effects of low-level laser therapy on reducing pain, edema, and trismus after orthognathic surgery: a systematic review.Lasers in medical science · 2022Pooled it
- A meta-analysis of pre- and postoperative corticosteroids for reducing the complications following facial reconstructive and aesthetic surgery.Brazilian journal of otorhinolaryngologyPooled it
- Trial
- The impact of orthodontic-surgical treatment on facial expressions-a four-dimensional clinical trial.Clinical oral investigations · 2023Trial
- Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial.Medicina oral, patologia oral y cirugia bucal · 2023Trial
- Comparison between orthopedic and surgical treatment of mandibular condylar fractures. An epidemiological and treatment outcomes research of the Maxillofacial Center in Cluj-Napoca, Romania.Medicine and pharmacy reports · 2026Article
- Evaluation, prevention, and treatment of inferior alveolar nerve injury in bilateral sagittal split mandibular osteotomy.Maxillofacial plastic and reconstructive surgery · 2025Review
- Analysis of Risk Factors and Preventive Measures on Postoperative Infection Rates in Orthognathic Surgery Patients: A Retrospective Study.Journal of pharmacy & bioallied sciences · 2025Article
- Risk of Permanent Dysfunction of Facial Nerves After Open Rigid Internal Fixation in the Treatment of Mandibular Condylar Process Fracture.Medical sciences (Basel, Switzerland) · 2025Article
- Photobiomodulation Therapy for Neurosensory Disturbances in Orthognathic Surgery Patients: A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Validity and Responsiveness of Measuring Facial Swelling With 3D Stereophotogrammetry in Patients After Bilateral Sagittal Split Osteotomy-A Prospective Clinimetric Study.International journal of biomedical imaging · 2025Article
- Comprehensive anaesthesia management strategies for orthognathic surgical procedure.Medicina oral, patologia oral y cirugia bucal · 2025Review
- Does mandibular osteotomy affect the infraorbital nerve? a prospective study.Clinical oral investigations · 2023Article
- Reliability of 3D Stereophotogrammetry for Measuring Postoperative Facial Swelling.Journal of clinical medicine · 2022Article
- Risk Factors for Prolonged Mechanical Ventilation and Delayed Extubation Following Bimaxillary Orthognathic Surgery: A Single-Center Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- A Prospective Randomized Study to Assess the Quality of Life in Post-Operative Recovery Phase in Patients Undergoing Surgery for Isolated Vertically Undisplaced Mandibular Parasymphysis Fracture Using Twin Mix Solution.Journal of maxillofacial and oral surgery · 2022Article
- Factors Influencing Clinical After Effects of Post Orthognathic Surgery - An Observational Clinical Study.Journal of pharmacy & bioallied sciences · 2021Article
- Maxillary sinus haziness and facial swelling following suction drainage in the maxilla after orthognathic surgery.Maxillofacial plastic and reconstructive surgery · 2020Article
- The Impact of the Use of Kinesio Taping Method on the Reduction of Swelling in Patients After Orthognathic Surgery: A Pilot Study.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Three-Dimensional Evaluation of the Effects of Kinesio Taping on Postoperative Swelling and Pain after Surgically Assisted Rapid Palatal Expansion.Journal of oral & maxillofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthognathic surgery is associated with considerable swelling and neurosensory disturbances. Serious swelling can lead to great physical and psychological strain. A randomized, prospective, controlled clinical trial was realized in order to evaluate the effect of a preoperative intravenous dexamethasone injection of 40 mg on postoperative swelling and neurosensory disturbances after orthognathic surgery.
methodsThirty-eight patients (27 male and 11 female) patients, all with the indication for an orthognathic surgery, were enrolled in this study (mean age: 27.63 years, range: 16-61 years) and randomly divided into two groups (study group/ control group). Both groups underwent either maxillary and/or mandibular osteotomies, resulting in three subgroups according to surgical technique (A: LeFort I osteotomy, B: bilateral sagittal split osteotomy (BSSO), C: bimaxillary osteotomy). The study group received a single preoperative intravenous injection of 40 mg dexamethasone. Facial edema was measured by 3D surface scans on the 1st, 2nd, 5th, 14th and 90th postoperative day. Furthermore, neurosensory disturbances on the 2nd, 5th, 14th and 90th postoperative day were investigated by thermal stimulation.
resultsFacial edema after LeFort I osteotomy, BSSO and bimaxillary osteotomy showed a significant decrease in the study group compared to the control group (P = 0.048, P = 0.045, P < 0.001). The influence of dexamethasone on neurosensory disturbances was not significant for the inferior alveolar nerve (P = 0.746) or the infraorbital nerve (P = 0.465).
conclusionsPatients undergoing orthognathic surgery should receive a preoperative injection of dexamethasone in order to control and reduce edema. However, there was no influence of dexamethasone on reduction of neurosensory disturbances.
trial registrationDRKS00009033 .
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