Evidence map›Paper›PMID 29115910›Full record

ArticleGlobal health action2017

Factors associated with long turnaround time for early infant diagnosis of HIV in Myanmar.

Soe Thiha, Hemant Deepak Shewade, Sairu Philip, Thet Ko Aung, Nang Thu Thu Kyaw, Myo Minn Oo, Khine Wut Yee Kyaw, May Wint War, Htun Nyunt Oo

Abstract read
In one paragraph

Article in Global health action, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soe Thihaa HIV Unit , International Union Against Tuberculosis and Lung Disease (The Union) , Mandalay , Myanmar.ORCID http://orcid.org/0000-0003-0263-136X
Hemant Deepak Shewadeb Department of Operational Research , International Union Against Tuberculosis and Lung Disease (The Union) , New Delhi , India.ORCID http://orcid.org/0000-0002-8242-1911
Sairu Philipc Department of Community Medicine , Government T.D. Medical College , Alappuzha , India.ORCID http://orcid.org/0000-0003-1531-9519
Thet Ko Aunga HIV Unit , International Union Against Tuberculosis and Lung Disease (The Union) , Mandalay , Myanmar.ORCID http://orcid.org/0000-0002-6222-7994
Nang Thu Thu Kyawd Department of Operational Research , International Union Against Tuberculosis and Lung Disease (The Union) , Mandalay , Myanmar.ORCID http://orcid.org/0000-0002-4849-579X
Myo Minn Ood Department of Operational Research , International Union Against Tuberculosis and Lung Disease (The Union) , Mandalay , Myanmar.ORCID http://orcid.org/0000-0003-4089-016X
Khine Wut Yee Kyawd Department of Operational Research , International Union Against Tuberculosis and Lung Disease (The Union) , Mandalay , Myanmar.ORCID http://orcid.org/0000-0003-0709-484X
May Wint Ware Public Health Laboratory, Department of Medical Services , Ministry of Health and Sports , Mandalay , Myanmar.
Htun Nyunt Oof National AIDS Program, Department of Public Health , Ministry of Health and Sports , Nay Pyi Taw , Myanmar.ORCID http://orcid.org/0000-0002-8464-7201

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA previous review of early infant diagnosis (EID) using polymerase chain reaction technology (PCR) under integrated HIV care (IHC) program in Myanmar revealed a low uptake of timely (within 6 to 8 weeks of babies' age) EID and a long turnaround time (TAT) of receiving results.

objectiveThis study aimed to determine the proportion and factors associated with the composite outcome of a long TAT (≥7 weeks; from sample collection to receipt of result by mother) or nonreceipt of result among HIV-exposed babies whose blood samples were collected for PCR at <9 months of age under the IHC program, Myanmar (2013-15).

methodsCohort study involving record review of routinely collected data. A predictive Poisson regression model with robust variance estimates was fitted for risk factors of long TAT or nonreceipt of result.

resultsBlood samples of 1 000 babies were collected; among them, long TAT or nonreceipt of results was seen in 690 (69%), and this was more than 50% across all subgroups. Babies with a mother's CD4 count of 100-350 cells/mm

conclusionsThe proportion of babies with long TAT or nonreceipt of result by the mother was high. Point-of-care testing for EID may reduce TAT/nonreceipt of results by the mother. Health system, laboratory, and logistic factors such as sample transportation, laboratory procedures, and result dispatching associated with long TAT should be further explored.

Indexed as

Early DiagnosisCohort StudiesFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMaleMyanmarRisk FactorsTime Factorsearly diagnosis/utilizationHIV-exposed babiesoperational researchSORT ITturnaround time

Identifiers

PMID29115910
PMCPMC5700493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.