Evidence map›Paper›PMID 29115900›Full record

ArticleDrug delivery2017

Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique.

Weiwei Wu, Yuangang Zu, Li Wang, Lingling Wang, Huimei Wang, Yuanyuan Li, Mingfang Wu, Xiuhua Zhao, Yujie Fu

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  6. Article
  7. Article
  8. Animals : an open access journal from MDPI · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Nanoencapsulation of apigenin with whey protein isolate: physicochemical properties,Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire · 2022
    Article
  17. Current Strategies and Potential Prospects for Nanoparticle-Mediated Treatment of Diabetic Nephropathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Weiwei Wua Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field (SAVER), Ministry of Education , Alkali Soil Natural Environmental Science Center (ASNESC), Northeast Forestry University , Harbin , China.
Yuangang Zub Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Li Wangb Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Lingling Wangb Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Huimei Wangb Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Yuanyuan Lib Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Mingfang Wub Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Xiuhua Zhaob Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Yujie Fub Key Laboratory of Forest Plant Ecology , Northeast Forestry University, Ministry of Education , Harbin , China.
Northeast Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work aimed to apply the liquid antisolvent precipitation (LAP) method for preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability of apigenin. The different experimental parameters on particle size were optimized through central composite design (CCD) using the Design-Expert

Indexed as

AnimalsAntineoplastic AgentsApigeninBiological AvailabilityCalorimetry, Differential ScanningCell Line, TumorChemical PrecipitationChemistry, PharmaceuticalDrug CompoundingFreeze DryingHep G2 CellsHumansMicroscopy, Electron, ScanningNanoparticlesParticle SizeRatsAntineoplastic AgentsApigeninSolventsantitumor activityApigeninapigenin nanoparticlesbioavailabilitysolubility

Identifiers

PMID29115900
PMCPMC8241174
OpenAlexW2767531132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.