Evidence map›Paper›PMID 29115868›Full record

Trial reportBrain injury2017

Longitudinal trajectories of post-concussive and depressive symptoms in adolescents with prolonged recovery from concussion.

Elizabeth Stein, Waylon Howard, Ali Rowhani-Rahbar, Frederick P Rivara, Douglas Zatzick, Carolyn A McCarty

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain injury, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth Steina Center for Child Health, Behavior and Development , Seattle Children's Research Institute , Seattle , WA, USA.
Waylon Howarda Center for Child Health, Behavior and Development , Seattle Children's Research Institute , Seattle , WA, USA.
Ali Rowhani-Rahbarb Department of Epidemiology , University of Washington , Seattle , WA, USA.
Frederick P Rivaraa Center for Child Health, Behavior and Development , Seattle Children's Research Institute , Seattle , WA, USA.
Douglas Zatzickc Harborview Injury Prevention and Research Center , University of Washington , Seattle , WA, USA.ORCID http://orcid.org/0000-0001-7339-1020
Carolyn A McCartya Center for Child Health, Behavior and Development , Seattle Children's Research Institute , Seattle , WA, USA.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1 TR002319
6 · The paper itself

Abstract

PRIMARY

objectiveTo investigate the symptom trajectories of depressive and post-concussive symptoms (PCS) in slow-to-recover adolescents to understand how the two sets of symptoms are related. RESEARCH

designWe used data from a randomized clinical trial of a collaborative care intervention for post-concussive symptoms to better understand how these two sets of symptoms change in parallel over 6 months. METHODS AND PROCEDURE: PCS and depressive symptom scores for 49 adolescents (ages 11-17) were measured at enrolment and after 1, 3, and 6 months. Latent growth curve modelling for parallel processes was used to simultaneously examine change in PCS and depressive symptoms over time and to evaluate the influence of one change process on the other. MAIN OUTCOMES AND

resultsOn average, patients enrolled 66 days following injury (Interquartile range (IQR) 43.5, 88.5). PCS and depressive symptoms were significantly associated at enrolment and over time, and both decreased over the course of 6 months. Higher PCS at enrolment predicted a greater decrease in depressive symptoms over time.

conclusionsOur results suggest that clinicians should screen for and treat depressive symptoms in patients with high post-concussive symptoms one month following injury.

Indexed as

AdolescentAthletic InjuriesBrain ConcussionChildDepressionFemaleHumansLongitudinal StudiesMaleModels, StatisticalNeuropsychological TestsPost-Concussion SyndromePsychiatric Status Rating ScalesRisk FactorsTime Factorsconcussiondepressionpediatricpost-concussive symptomstraumatic brain injury

Identifiers

PMID29115868
PMCPMC6194147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.