Evidence map›Paper›PMID 29115287›Full record

ArticleJournal of exposure science & environmental epidemiology2018

Consumer product chemical weight fractions from ingredient lists.

Kristin K Isaacs, Katherine A Phillips, Derya Biryol, Kathie L Dionisio, Paul S Price

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. High Throughput Risk and Impact Screening of Chemicals in Consumer Products.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  2. Article
  3. Article
  4. New Approach Methodologies for Exposure Science.Current opinion in toxicology · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristin K IsaacsU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, E205-02, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.
Katherine A PhillipsU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, E205-02, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.
Derya BiryolU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, E205-02, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.
Kathie L DionisioU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, E205-02, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.
Paul S PriceU.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, E205-02, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Assessing human exposures to chemicals in consumer products requires composition information. However, comprehensive composition data for products in commerce are not generally available. Many consumer products have reported ingredient lists that are constructed using specific guidelines. A probabilistic model was developed to estimate quantitative weight fraction (WF) values that are consistent with the rank of an ingredient in the list, the number of reported ingredients, and labeling rules. The model provides the mean, median, and 95% upper and lower confidence limit WFs for ingredients of any rank in lists of any length. WFs predicted by the model compared favorably with those reported on Material Safety Data Sheets. Predictions for chemicals known to provide specific functions in products were also found to reasonably agree with reported WFs. The model was applied to a selection of publicly available ingredient lists, thereby estimating WFs for 1293 unique ingredients in 1123 products in 81 product categories. Predicted WFs, although less precise than reported values, can be estimated for large numbers of product-chemical combinations and thus provide a useful source of data for high-throughput or screening-level exposure assessments.

Indexed as

Product LabelingConsumer Product SafetyEnvironmental ExposureHumansInorganic ChemicalsMaterial Safety Data SheetsModels, StatisticalMonte Carlo MethodOrganic ChemicalsRisk AssessmentUnited StatesUnited States Food and Drug AdministrationInorganic ChemicalsOrganic Chemicals

Identifiers

PMID29115287
PMCPMC6082127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.