Evidence map›Paper›PMID 29115081›Full record

ArticleJournal of Korean medical science2017

Verification of Current Risk Scores for Kawasaki Disease in Korean Children.

Jaeeun Shin, Heeyoung Lee, Lucy Eun

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  7. Review
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  9. Pediatric expert consensus on the application of glucocorticoids in Kawasaki disease.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaeeun ShinDivision of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-3089-9347
Heeyoung LeeDivision of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-8294-0914
Lucy EunDivision of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea. lucyeun@yuhs.ac.ORCID https://orcid.org/0000-0002-4577-3168

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to evaluate and assess the compatibility of current risk scoring systems from Japan that were developed to predict intravenous immunoglobulin (IVIG) resistance in patients with Kawasaki disease (KD). The authors previously investigated another prediction model for patients with refractory KD in Korea. A retrospective study involving 350 patients with KD who were admitted between January 2014 and December 2015 was performed. Patients younger than 2 years were excluded for the propensity score matching in this study. Patients were classified into IVIG responders and IVIG resistance groups. The well-known Harada, Kobayashi, and Egami risk scores were calculated for each patient, and the proportion of high-risk patients was compared between the two groups for each risk score. Logistic regression analysis revealed that platelets, C-reactive protein (CRP) levels, and aspartate aminotransferase levels were independent predictors of IVIG resistance. Multivariate analysis suggested that platelets and CRP were risk factors. Risk-scoring systems from Japan have good specificity but low sensitivity. Among the three risk scoring systems, the Kobayashi risk score demonstrated significant differences between the IVIG resistance and IVIG responder groups in Korean patients with KD. It is very important to identify IVIG-resistant patients to protect them from ongoing coronary arterial lesion(s); therefore, early prediction and timely optimal additional treatment is of significant benefit. It would be helpful to construct a highly sensitive, exclusive scoring system for Korean patients with KD.

Indexed as

Age FactorsAsian PeopleAspartate AminotransferasesBlood PlateletsChild, PreschoolC-Reactive ProteinDrug ResistanceFemaleHumansImmunoglobulins, IntravenousInfantMaleMucocutaneous Lymph Node SyndromeMultivariate AnalysisPredictive Value of TestsRepublic of KoreaAspartate AminotransferasesC-Reactive ProteinImmunoglobulins, IntravenousIntravenous ImmunoglobulinKawasaki DiseasePredictionResistanceRisk Score

Identifiers

PMID29115081
PMCPMC5680498

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.