Evidence map›Paper›PMID 29115043›Full record

ArticleMicrobial biotechnology2018

Harnessing novel chromosomal integration loci to utilize an organosolv-derived hemicellulose fraction for isobutanol production with engineered Corynebacterium glutamicum.

Julian Lange, Felix Müller, Ralf Takors, Bastian Blombach

Abstract read
In one paragraph

Article in Microbial biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. EngineeringBiodesign research · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Review
  9. Exploring the Potential ofFrontiers in bioengineering and biotechnology · 2021
    Article
  10. Coenzyme QFrontiers in bioengineering and biotechnology · 2021
    Article
  11. A Timed Off-Switch for Dynamic Control of Gene Expression inFrontiers in bioengineering and biotechnology · 2021
    Article
  12. COmBio · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julian LangeInstitute of Biochemical Engineering, University of Stuttgart, D-70569, Stuttgart, Germany.
Felix MüllerInstitute of Biochemical Engineering, University of Stuttgart, D-70569, Stuttgart, Germany.
Ralf TakorsInstitute of Biochemical Engineering, University of Stuttgart, D-70569, Stuttgart, Germany.
Bastian BlombachInstitute of Biochemical Engineering, University of Stuttgart, D-70569, Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A successful bioeconomy depends on the manifestation of biorefineries that entirely convert renewable resources to valuable products and energies. Here, the poorly exploited hemicellulose fraction (HF) from beech wood organosolv processing was applied for isobutanol production with Corynebacterium glutamicum. To enable growth of C. glutamicum on HF, we integrated genes required for D-xylose and l-arabinose metabolization into two of 16 systematically identified and novel chromosomal integration loci. Under aerobic conditions, this engineered strain CArXy reached growth rates up to 0.34 ± 0.02 h

Indexed as

Genetic LociArabinoseButanolsCorynebacterium glutamicumGene Knock-In TechniquesMetabolic EngineeringMetabolic Networks and PathwaysPolysaccharidesXyloseArabinoseButanolshemicelluloseisobutyl alcoholPolysaccharidesXylose

Identifiers

PMID29115043
PMCPMC5743825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.