Evidence map›Paper›PMID 29114497›Full record

ArticleFrontiers in cellular and infection microbiology2017

KCTD5 and Ubiquitin Proteasome Signaling Are Required for

Alhejandra Álvarez, Felipe Uribe, Jimena Canales, Cristóbal Romero, Andrea Soza, María A Peña, Marcelo Antonelli, Oscar Almarza, Oscar Cerda, Héctor Toledo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
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  4. KCells · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alhejandra ÁlvarezMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Felipe UribeMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Jimena CanalesMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Cristóbal RomeroMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Andrea SozaDepartment of Biological and Chemical Sciences, Faculty of Science, Universidad San Sebastián, Santiago, Chile.
María A PeñaMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Marcelo AntonelliMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Oscar AlmarzaMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Oscar CerdaMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
Héctor ToledoMolecular and Cellular Biology Program, Faculty of Medicine, Instituto de Ciencias Biomédicas (ICBM), Universidad de Chile, Santiago, Chile.
University of Chile · CLMillennium Nucleus of Ion Channel Associated Diseases · CLSan Sebastián University · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to establish infection, bacterial pathogens modulate host cellular processes by using virulence factors, which are delivered from the bacteria to the host cell leading to cellular reprogramming. In this context, several pathogens regulate the ubiquitin proteasome system in order to regulate the cellular effectors required for their successful colonization and persistance. In this study, we investigated how

Indexed as

Signal TransductionAcetylcysteineAdhesins, BacterialAntigens, BacterialBacterial ProteinsCell LineCoculture TechniquesCullin ProteinsEpithelial CellsGastric MucosaHelicobacter InfectionsHelicobacter pyloriHost-Pathogen InteractionsHumansLysosomesPotassium ChannelsAcetylcysteineAdhesins, BacterialAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriCullin ProteinsKCTD5 protein, humanlactacystinPotassium ChannelsProteasome Endopeptidase ComplexUbiquitinVacA protein, Helicobacter pyloriVirulence FactorsCagACullin-3Helicobacter pyloriKCTD5ubiquitin proteasome systemVacA

Identifiers

PMID29114497
PMCPMC5660694
OpenAlexW2765869938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.