Evidence map›Paper›PMID 29114259›Full record

ArticleFrontiers in genetics2017

Identification of Splicing Quantitative Trait Loci (sQTL) in

Wen Qu, Katherine Gurdziel, Roger Pique-Regi, Douglas M Ruden

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Viruses in LaboratoryViruses · 2023
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Lead ModulatesFrontiers in genetics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wen QuLaboratory of Epigenomics, Department of Pharmacology, C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI, United States.
Katherine GurdzielDepartment of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States.
Roger Pique-RegiCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, United States.
Douglas M RudenLaboratory of Epigenomics, Department of Pharmacology, C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI, United States.
Wayne State University · US

Funding

Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Prenatal Exposures and Child Health Outcomes: A Statewide StudyUG3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI BARONE, CHARLES JAMES, ELLIOTT, MICHAEL R. · 2016 to 2024
$12.9M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2014 to 2021
$10.1M
QTL AND MICROARRAY MAPPING LEAD SENSITIVITY GENESR01ES012933 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2004 to 2015
$3.4M
Functional Characterization of the Genetic and Environmental Determinants of Complex TraitsR01GM109215 · NIGMS · WAYNE STATE UNIVERSITY · PI Francesca Luca, Roger Pique-Regi · 2014 to 2026
$3.2M
NovaSeq Shared Instrumentation Grant for Wayne State UniversityS10OD025170 · OD · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2018 to 2018
$600k
Effects of Lead on Neuronal Differentiation in Human Embryonic Stem CellsR21ES021983 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2012 to 2013
$413k
NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R01 ES012933NIEHS NIH HHS R21 ES021983NIGMS NIH HHS R01 GM109215NIH HHS S10 OD025170NIH HHS UG3 OD023285NIH HHS UH3 OD023285
6 · The paper itself

Abstract

Lead (Pb) poisoning has been a major public health issue globally and the recent Flint water crisis has drawn nation-wide attention to its effects. To better understand how lead plays a role as a neurotoxin, we utilized the

Indexed as

developmental lead exposureDrosophila melanogasterDrosophila synthetic population resource (DSPR)RNA-seqsplicing quantitative trait loci (sQTL or splice QTL)toxicogenomics

Identifiers

PMID29114259
PMCPMC5660682
OpenAlexW2765926534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.