Evidence map›Paper›PMID 29114215›Full record

ArticleFrontiers in computational neuroscience2017

Feasibility of 3D Reconstruction of Neural Morphology Using Expansion Microscopy and Barcode-Guided Agglomeration.

Young-Gyu Yoon, Peilun Dai, Jeremy Wohlwend, Jae-Byum Chang, Adam H Marblestone, Edward S Boyden

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Young-Gyu YoonDepartment of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States.
Peilun DaiMIT Media Lab, MIT, Cambridge, MA, United States.
Jeremy WohlwendDepartment of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States.
Jae-Byum ChangMIT Media Lab, MIT, Cambridge, MA, United States.
Adam H MarblestoneMIT Media Lab, MIT, Cambridge, MA, United States.
Edward S BoydenMIT Media Lab, MIT, Cambridge, MA, United States.

Funding

Center for Genomically Engineered OrgansRM1HG008525 · NHGRI · HARVARD MEDICAL SCHOOL · PI CHURCH, GEORGE M · 2015 to 2019
$10.2M
Millisecond-Timescale Whole-Brain Neural Activity Mapping in Health and DiseaseDP1NS087724 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BOYDEN, EDWARD S. · 2013 to 2017
$3.9M
An Accessible Optical Toolbox for Saturated Nanoscale Analysis of Neural ArchitectureR01MH110932 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYDEN, EDWARD S., CAI, DAWEN · 2016 to 2019
$2.8M
Whole Brain Nanoscale Preservation/ImagingR41MH112318 · NIMH · NECTOME, INC. · PI MCINTYRE, ROBERT · 2016 to 2017
$916k
NHGRI NIH HHS RM1 HG008525NIMH NIH HHS R01 MH110932NIMH NIH HHS R41 MH112318NINDS NIH HHS DP1 NS087724
6 · The paper itself

Abstract

We here introduce and study the properties, via computer simulation, of a candidate automated approach to algorithmic reconstruction of dense neural morphology, based on simulated data of the kind that would be obtained via two emerging molecular technologies-expansion microscopy (ExM) and

Indexed as

3-D reconstructionagglomerationconvolutional neural networkexpansion microscopyneural morphologyRNA barcode

Identifiers

PMID29114215
PMCPMC5660712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.