Evidence map›Paper›PMID 29114048›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

New free-exchange model of EmrE transport.

Anne E Robinson, Nathan E Thomas, Emma A Morrison, Bryan M Balthazor, Katherine A Henzler-Wildman

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Multimodal dynamics control activity of a glial glutamate transporter.bioRxiv : the preprint server for biology · 2026
    Article
  4. Protonated Structure of EmrE Reveals C-terminal Tail Gating Mechanism.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. In Situ Light-driven pH Modulation for NMR Studies.Angewandte Chemie (International ed. in English) · 2025
    Article
  8. Review
  9. Article
  10. H-NS controls the susceptibility ofFrontiers in veterinary science · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Peripheral positions encode transport specificity in the small multidrug resistance exporters.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. A Small Multidrug Resistance Transporter inbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anne E RobinsonDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Nathan E ThomasDepartment of Biochemistry, University of Wisconsin at Madison, Madison, WI 53706.
Emma A MorrisonDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Bryan M BalthazorDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Katherine A Henzler-WildmanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110; henzlerwildm@wisc.edu.ORCID 0000-0002-5295-2121
Washington University in St. Louis · USUniversity of Wisconsin–Madison · US

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
TRANSPORT MECHANISM OF THE MULTIDRUG RESISTANCE EFFLUX PROTEIN, EMRER01GM095839 · NIGMS · WASHINGTON UNIVERSITY · PI HENZLER-WILDMAN, KATHERINE ANNE · 2011 to 2020
$3.1M
NIGMS NIH HHS R01 GM095839NIGMS NIH HHS T32 GM007215
6 · The paper itself

Abstract

EmrE is a small multidrug resistance transporter found in

Indexed as

ProtonsAntiportersBinding SitesBiological TransportDicyclohexylcarbodiimideDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli ProteinsGene ExpressionHydrogen-Ion ConcentrationKineticsMolecular Dynamics SimulationOnium CompoundsOrganophosphorus CompoundsPhosphatidylcholinesPhosphatidylglycerols1-palmitoyl-2-oleoylglycero-3-phosphoglycerol1-palmitoyl-2-oleoylphosphatidylcholineAntiportersDicyclohexylcarbodiimideEmrE protein, E coliEscherichia coli ProteinsOnium CompoundsOrganophosphorus CompoundsPhosphatidylcholinesPhosphatidylglycerolsProteolipidsproteoliposomesProtonsRecombinant ProteinstetraphenylphosphoniumXenobioticscoupled transportmembrane proteinmultidrug transportNMRprotein dynamics

Identifiers

PMID29114048
PMCPMC5703289
OpenAlexW2768093345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.