Evidence map›Paper›PMID 29113983›Full record

ArticleDiabetes care2018

FGF23 Concentration and

Gary C Chan, Jasmin Divers, Gregory B Russell, Carl D Langefeld, Lynne E Wagenknecht, Fang-Chi Hsu, Jianzhao Xu, S Carrie Smith, Nicholette D Palmer, Pamela J Hicks and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Journal of the American Society of Nephrology : JASN · 2019
    Pooled it
  3. Trial
  4. Review
  5. Phosphate and fibroblast growth factor 23 in diabetes.Clinical science (London, England : 1979) · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. APOL1 Nephropathy Risk Alleles and Mortality in African American Adults: A Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Gary C ChanSection on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Jasmin DiversDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Gregory B RussellDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Carl D LangefeldDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Lynne E WagenknechtDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Fang-Chi HsuDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Jianzhao XuDepartment of Biochemistry, Center for Genomics and Personalized Medicine Research, and Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.
S Carrie SmithDepartment of Biochemistry, Center for Genomics and Personalized Medicine Research, and Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.
Nicholette D PalmerDepartment of Biochemistry, Center for Genomics and Personalized Medicine Research, and Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.ORCID 0000-0001-8883-2511
Pamela J HicksDepartment of Biochemistry, Center for Genomics and Personalized Medicine Research, and Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.
Donald W BowdenDepartment of Biochemistry, Center for Genomics and Personalized Medicine Research, and Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.
Thomas C RegisterDepartment of Pathology, Wake Forest School of Medicine, Winston-Salem, NC.
Lijun MaSection on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
J Jeffrey CarrDepartment of Radiology, Vanderbilt University School of Medicine, Nashville, TN.
Barry I FreedmanSection on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC bfreedma@wakehealth.edu.ORCID 0000-0003-0275-5530
Wake Forest University · USVanderbilt University · US

Funding

Subclinical CVD in African American Type 2 DiabeticsR01DK071891 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FREEDMAN, BARRY IRA · 2007 to 2016
$4.5M
Epidemiology of cardiovascular disease in diabetesR01HL067348 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BOWDEN, DONALD W · 2001 to 2004
$4.3M
Genetics of Bone and Vascular Calcium in Type 2 DiabetesR01AR048797 · NIAMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CARR, JOHN JEFFREY · 2001 to 2004
$1.3M
NHLBI NIH HHS R01 HL067348NIAMS NIH HHS R01 AR048797NIDDK NIH HHS R01 DK071891
6 · The paper itself

Abstract

objectiveCardiovascular and renal complications contribute to higher mortality in patients with diabetes. We assessed novel and conventional predictors of mortality in African American-Diabetes Heart Study (AA-DHS) participants. RESEARCH DESIGN AND

methodsAssociations between mortality and subclinical atherosclerosis, urine albumin-to-creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), plasma fibroblast growth factor 23 (FGF23) concentration, African ancestry proportion, and apolipoprotein L1 genotypes (

resultsAt baseline, participants were 55.6% female with median (25th, 75th percentile) age 55 years (49.0, 62.0), diabetes duration 8 years (5.0, 13.0), glycosylated hemoglobin 60.7 mmol/mol (48.6, 76.0), eGFR 91.3 mL/min/1.73 m

conclusionsAccounting for conventional risk factors, higher FGF23 concentrations and

Indexed as

AlbuminuriaApolipoprotein L1AtherosclerosisBlack or African AmericanCohort StudiesCreatinineDiabetes Mellitus, Type 2FemaleFibroblast Growth Factor-23Fibroblast Growth FactorsFollow-Up StudiesGenotyping TechniquesGlomerular Filtration RateGlycated HemoglobinHumansKidney Function TestsAPOL1 protein, humanApolipoprotein L1CreatinineFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsGlycated Hemoglobin

Identifiers

PMID29113983
PMCPMC5741152
OpenAlexW2767245973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.