Evidence map›Paper›PMID 29113976›Full record

ArticleEMBO molecular medicine2018

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8

Teck-Hui Teo, Shanshan W Howland, Carla Claser, Sin Yee Gun, Chek Meng Poh, Wendy Wl Lee, Fok-Moon Lum, Lisa Fp Ng, Laurent Rénia

Open access · goldAbstract read
In one paragraph

Article in EMBO molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  7. Article
  8. SARS-CoV-2 decreases malaria severity in co-infected rodent models.Frontiers in cellular and infection microbiology · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Current research in immunology · 2021
    Article
  14. The impact of COVID-19 pandemic on malaria elimination.Parasite epidemiology and control · 2020
    Review
  15. Article
  16. Review
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  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Teck-Hui TeoSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Shanshan W HowlandSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Carla ClaserSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Sin Yee GunSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Chek Meng PohSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Wendy Wl LeeSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Fok-Moon LumSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-5645-7048
Lisa Fp NgSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore lisa_ng@immunol.a-star.edu.sg renia_laurent@immunol.a-star.edu.sg.ORCID 0000-0003-4071-5222
Laurent RéniaSingapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore lisa_ng@immunol.a-star.edu.sg renia_laurent@immunol.a-star.edu.sg.ORCID 0000-0003-0349-1557
Agency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arboviral diseases have risen significantly over the last 40 years, increasing the risk of co-infection with other endemic disease such as malaria. However, nothing is known about the impact arboviruses have on the host response toward heterologous pathogens during co-infection. Here, we investigate the effects of Chikungunya virus (CHIKV) co-infection on the susceptibility and severity of malaria infection. Using the

Indexed as

AnimalsBrainCD8-Positive T-LymphocytesCell MovementChikungunya FeverChikungunya virusCoinfectionFemaleMalaria, CerebralMaleMiceMice, Inbred C57BLNeuropathologyPlasmodium bergheiProtective FactorsCD8+ T‐cell traffickingChikungunyaco‐infectionmalaria

Identifiers

PMID29113976
PMCPMC5760855
OpenAlexW2767319626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.