Evidence map›Paper›PMID 29113898›Full record

ArticleNeuropharmacology2018

Finding order in chemical chaos - Continuing characterization of synthetic cannabinoid receptor agonists.

Julie A Marusich, Jenny L Wiley, Timothy W Lefever, Purvi R Patel, Brian F Thomas

Abstract read
In one paragraph

Article in Neuropharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. ΔDrug and alcohol dependence reports · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Cannabinoids in the Pathophysiology of Skin Inflammation.Molecules (Basel, Switzerland) · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julie A MarusichRTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, United States.
Jenny L WileyRTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, United States.
Timothy W LefeverRTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, United States.
Purvi R PatelRTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, United States.
Brian F ThomasRTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, United States. Electronic address: bft@rti.org.
RTI International · US

Funding

THC RECEPTORSR01DA003672 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILEY, JENNY L. · 1985 to 2018
$4.9M
Investigation of Synthetic Cannabinoid Exposures and Pharmacological ConsequencesR01DA040460 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI RANGAN MAITRA, Yanan Zhang · 2016 to 2026
$4.5M
THC RECEPTORSR37DA003672 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MARTIN, BILLY R · 1997 to 2006
$2.8M
NIDA NIH HHS R01 DA003672NIDA NIH HHS R01 DA040460NIDA NIH HHS R37 DA003672
6 · The paper itself

Abstract

Diversion of synthetic cannabinoids from the lab to drugs of abuse has become increasingly prevalent in recent years. Moreover, as earlier synthetic cannabinoids were banned, manufacturers introduced a new supply of novel compounds to serve as replacements. Hence, the chemical diversity of synthetic cannabinoid analogs has also rapidly increased. The present study examined 8 new synthetic cannabinoids: AM-1220, AM-2232, AM-2233, AM-679, EAM-2201, JWH-210, JHW-251, and MAM-2201. Each compound was assessed for binding affinity and functional activation of CB

Indexed as

Discrimination, PsychologicalAnimalsCannabinoid Receptor AgonistsCannabinoidsDesigner DrugsDose-Response Relationship, DrugGuanosine 5'-O-(3-Thiotriphosphate)MaleMiceMice, Inbred C57BLProtein BindingReceptors, CannabinoidTritiumCannabinoid Receptor AgonistsCannabinoidsDesigner DrugsGuanosine 5'-O-(3-Thiotriphosphate)Receptors, CannabinoidTritiumAbuse liabilityDrug discriminationReceptor bindingSynthetic cannabinoidsΔ;(9)-tetrahydrocannabinol

Identifiers

PMID29113898
PMCPMC5934329
OpenAlexW2766144582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.