Evidence map›Paper›PMID 29113559›Full record

ArticleToxicologic pathology2017

Proceedings of the 2017 National Toxicology Program Satellite Symposium.

Susan A Elmore, Famke Aeffner, Dinesh S Bangari, Torrie A Crabbs, Stacey Fossey, Shayne C Gad, Wanda M Haschek, Jessica S Hoane, Kyathanahalli Janardhan, Ramesh C Kovi and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Toxicologic pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity.Toxicon : official journal of the International Society on Toxinology · 2019
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Susan A Elmore1 Cellular and Molecular Pathology Branch, National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.
Famke Aeffner2 Amgen, Inc., South San Francisco, California, USA.
Dinesh S Bangari3 Sanofi Genzyme, Framingham, Massachusetts, USA.
Torrie A Crabbs4 Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA.
Stacey Fossey5 AbbVie Bioresearch Center, Worcester, Massachusetts, USA.
Shayne C Gad6 Gad Consulting Services, Raleigh, North Carolina, USA.
Wanda M Haschek7 Department of Pathobiology, University of Illinois, Urbana, Illinois, USA.
Jessica S Hoane8 Charles River Laboratories, Inc., Durham, North Carolina, USA.
Kyathanahalli Janardhan9 Integrated Laboratory Systems, Inc., Research Triangle Park, North Carolina, USA.
Ramesh C Kovi4 Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA.
Gail Pearse10 GlaxoSmithKline, Ware, Hertfordshire, United Kingdom.
Lyn M Wancket11 NAMSA, Northwood, Ohio, USA.
Erin M Quist4 Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA.
Triangle · USAbbVie (United States) · USAmgen (United States) · USCharles River Laboratories (United States) · USExperimental Pathology Laboratories · USGad Consulting Services (United States) · USGlaxoSmithKline (United Kingdom) · GBIntegrated Laboratory Systems, Inc. · USNational Institutes of Health · USNorthwood University · USUniversity of Illinois Urbana-Champaign · US

Funding

CMPB Pathology Support GroupZICES102505 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI HERBERT, RONALD · 2014 to 2021
$67.7M
Intramural NIH HHS Z99 ES999999
6 · The paper itself

Abstract

The 2017 annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri," was held in Montreal, Quebec, Canada at the Society of Toxicologic Pathology's 36th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included renal papillary degeneration in perinatally exposed animals, an atriocaval mesothelioma, an unusual presentation of an alveolar-bronchiolar carcinoma, a paraganglioma of the organ of Zuckerkandl (also called an extra-adrenal pheochromocytoma), the use of human muscle samples to illustrate the challenges of manual scoring of fluorescent staining, intertubular spermatocytic seminomas, medical device pathology assessment and discussion of the approval process, collagen-induced arthritis, incisor denticles, ameloblast degeneration and poorly mineralized enamel matrix, connective tissue paragangliomas, microcystin-LR toxicity, perivascular mast cells in the forebrain thalamus unrelated to treatment, and 2 cases that provided a review of the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) bone nomenclature and recommended application of the terminology in routine nonclinical toxicity studies.

Indexed as

Congresses as TopicDiagnostic Techniques and ProceduresPathologySocieties, ScientificToxicologyAnimalsHumansImage Processing, Computer-AssistedQuebecatriocaval mesotheliomacollagen-induced arthritis modeldigital image analysisincisor denticleINHANDmedical device evaluationmicrocystin-LRneural mast cellsNTP Satellite Symposiumparagangliomaperinatal nephrotoxicosisspermatocytic seminoma

Identifiers

PMID29113559
PMCPMC5743204
OpenAlexW2917270236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.