Evidence map›Paper›PMID 29113556›Full record

ArticleStem cells and development2018

Phospholipase D Family Member 6 Is a Surface Marker for Enrichment of Undifferentiated Spermatogonia in Prepubertal Boars.

Pengfei Zhang, Yuwei Qin, Yi Zheng, Wenxian Zeng

Open access · greenAbstract read
In one paragraph

Article in Stem cells and development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Single-Cell RNA Sequencing Reveals an Atlas of Meihua Pig Testis Cells.Animals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. International journal of fertility & sterility · 2020
    Article
  7. Article
  8. Progress inZoological research · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pengfei Zhang1 College of Animal Science and Technology, Northwest A&F University , Shaanxi, China .
Yuwei Qin1 College of Animal Science and Technology, Northwest A&F University , Shaanxi, China .
Yi Zheng2 Center for Reproductive Medicine, Amsterdam Research Institute Reproduction and Development, Academic Medical Centre, University of Amsterdam , Amsterdam, the Netherlands .
Wenxian Zeng1 College of Animal Science and Technology, Northwest A&F University , Shaanxi, China .
University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermatogonial stem cells (SSCs) have a functional ability to maintain self-renewal and sustain production of spermatozoa throughout the reproductive lifespan of a male. Studies on SSCs can thus better the understandings of spermatogenesis and unravel the mechanisms for self-renewal and differentiation of male germline stem cells. However, the rarity of SSCs in the testis and the lack of reliable surface markers obstruct the related study and further application of SSCs. This is especially the case in livestock animals. In this study, we identified that phospholipase D family member 6 (PLD6) is a surface marker for undifferentiated spermatogonia in boar testes. By magnetic-activated cell sorting, PLD6

Indexed as

AnimalsBiomarkersCell Culture TechniquesCell DifferentiationMaleMiceMitochondrial ProteinsPhospholipase DSpermatogenesisSpermatogoniaStem CellsSwineTestisTransplantation, HeterologousBiomarkersMitochondrial ProteinsmitoPLD protein, mousePhospholipase Dboar testisfeeder-free cultureMACSPLD6undifferentiated spermatogonia

Identifiers

PMID29113556
PMCPMC5756458
OpenAlexW2767796542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.