Evidence map›Paper›PMID 29113374›Full record

ArticleOncotarget2017

Meta-analysis of the association between SCARB1 polymorphism and fasting blood lipid levels.

Li-Fang Ye, Ya-Ru Zheng, Qing-Gang Zhang, Jian-Wu Yu, Li-Hong Wang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li-Fang YeDepartment of Cardiovascular Sciences, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Ya-Ru ZhengDepartment of Cardiovascular Sciences, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Qing-Gang ZhangDepartment of Cardiovascular Sciences, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Jian-Wu YuDepartment of Cardiovascular Sciences, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Li-Hong WangDepartment of Cardiovascular Sciences, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Zhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have shown that the scavenger receptor class B type 1 (SCARB1) rs5888 polymorphism impacts fasting blood lipid levels differently in men and women. A meta-analysis and statistical tests was therefore performed to determine the relationship between the rs5888 polymorphism and lipid levels in men and women. Twelve studies with 12,147 subjects were selected for this study. In a dominant model, the CT+TT genotype group had lower triglyceride levels than the CC group in men (standardized mean difference (SMD): -0.11; 95% confidence interval (CI): -0.21 to -0.02;

Indexed as

lipidpolymorphismscavenger receptor class B type 1sex

Identifiers

PMID29113374
PMCPMC5655269
OpenAlexW2755700841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.