Evidence map›Paper›PMID 29113339›Full record

ArticleOncotarget2017

A new model to predict intravenous immunoglobin-resistant Kawasaki disease.

Wang Hua, Yameng Sun, Ying Wang, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang, Fangqi Gong

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wang Hua *Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Yameng Sun *Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Ying WangChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Songling FuChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Wei WangChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Chunhong XieChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Yiying ZhangChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.
Fangqi GongChildren's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo clarify the independent risk factors and construct predictive model for intravenous immunoglobin (IVIG)-resistant KD (IVIGRKD).

resultsThe ratio of male to female in the overall samples was 1.62:1 and the incidence of IVIGR was 17.9%. Multivariate regression analysis showed that the OR (95% CI) values of fever duration ≥ 7 days, delayed diagnosis, gamma-glutamyl transferase ≥ 25 U/L, serum sodium ≤ 135 mmol/L, neutrophil-to-lymphocyte ratio ≥ 2.8 and platelets ≤ 350 × 10 MATERIALS AND

methodsA total of 2,126 KD cases were enrolled in this study. Clinical indicators showing significant differences were screened using univariate analysis, and the independent risk factors were further elucidated using multivariate regression analysis. A new model was constructed, and the predictive ability was evaluated with the area under the curve (AUC) value and the sensitivity and specificity by using the receiver operating characteristic (ROC) curve.

conclusionsThe new model for predicting IVIGRKD in this study is superior to those reported previously, and further analysis of patients with IVIGRKD younger than 6 months old allowed optimization of the predictive model.

Indexed as

independent risk factorsIVIG resistantKawasaki diseasepredictive model

Identifiers

PMID29113339
PMCPMC5655234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.