Evidence map›Paper›PMID 29113229›Full record

ArticleOncology letters2017

Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma.

Tingting Chen, Lan Zhou, Hua Li, Yuan Tian, Junqin Li, Lihua Dong, Yuhua Zhao, Dapeng Wei

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Increased Expression of LIPC Is Associated with Aggressive Phenotype of Borrmann Type 4 Gastric Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  11. Article
  12. Fatty Acid Synthase: An Emerging Target in Cancer.Molecules (Basel, Switzerland) · 2020
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tingting ChenDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Lan ZhouDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Hua LiDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Yuan TianWest China School of Medicine/West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Junqin LiDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Lihua DongDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Yuhua ZhaoDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Dapeng WeiDepartment of Basic and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate changes in the expression of ErbBs during epithelial-mesenchymal transition (EMT) of breast cancer cells and its association with the expression of fatty acid synthase (FASN). MCF-7-MEK5 cells were used as the experimental model, while MCF-7 cells were used as a control. Tumor cells were implanted into nude mice for

Indexed as

breast cancerclinicopathological characteristicsepithelial-mesenchymal transitionErbB1-4fatty acid synthase

Identifiers

PMID29113229
PMCPMC5661422
OpenAlexW2755356269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.