Evidence map›Paper›PMID 29113189›Full record

ArticleOncology letters2017

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene

Patricia Adamo, Sean Porazinski, Shavanthi Rajatileka, Samantha Jumbe, Rachel Hagen, Man-Kim Cheung, Ian Wilson, Michael R Ladomery

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Patricia AdamoFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Sean PorazinskiFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Shavanthi RajatilekaFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Samantha JumbeFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Rachel HagenFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Man-Kim CheungFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Ian WilsonFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
Michael R LadomeryFaculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.
University of the West of England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oncogene ETS-related gene (ERG) encodes a transcription factor with roles in the regulation of haematopoiesis, angiogenesis, vasculogenesis, inflammation, migration and invasion. The

Indexed as

ERGprostate cancerPTENTMPRSS2 fusion

Identifiers

PMID29113189
PMCPMC5654480
OpenAlexW2745757975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.