ArticleOncology letters2017
Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27.
Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Bibliometric analysis of RNA-binding proteins in osteosarcoma: unraveling research trends and hotspots.Frontiers in immunology · 2025Pooled it
- The cellular landscape of druggable RNA-binding proteins.Nature reviews. Drug discovery · 2026Review
- Musashi-1 regulates cell cycle and confers resistance to cisplatin treatment in Group 3/4 medulloblastomas cells.Human cell · 2023Article
- Genome-wide identification of alternative splicing and splicing regulated in immune infiltration in osteosarcoma patients.Frontiers in genetics · 2023Article
- Functional Role of RBP in Osteosarcoma: Regulatory Mechanism and Clinical Therapy.Analytical cellular pathology (Amsterdam) · 2023Review
- LncRNA LINC00525 suppresses p21 expression via mRNA decay and triplex-mediated changes in chromatin structure in lung adenocarcinoma.Cancer communications (London, England) · 2021Article
- Expression of Musashi-1 Increases in Bone Healing.International journal of molecular sciences · 2021Article
- Article
- Interplay among p21Scientific reports · 2020Article
- Review
- Molecular entrapment by RNA: an emerging tool for disrupting protein-RNA interactionsRNA biology · 2020Article
- LINC01094 Down-Regulates miR-330-3p and Enhances the Expression of MSI1 to Promote the Progression of Glioma.Cancer management and research · 2020Article
- [Musashi-1 positively regulates growth and proliferation of hepatoma cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- Knockdown of MSI1 inhibits the proliferation of human oral squamous cell carcinoma by inactivating STAT3 signaling.International journal of molecular medicine · 2019Article
- Expression of Musashi-1 During Osteogenic Differentiation of Oral MSC: An In Vitro Study.International journal of molecular sciences · 2019Article
- Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation.Neoplasia (New York, N.Y.) · 2019Article
- RBMS2 inhibits the proliferation by stabilizing P21 mRNA in breast cancer.Journal of experimental & clinical cancer research : CR · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteosarcoma is the most common type of primary bone cancer in children and adolescents, but its mechanism remains unclear. Musashi RNA-binding protein 1 (MSI1) is highly expressed in certain cancer types and functions as a putative progenitor/stem cell marker. In the present study, it was demonstrated that MSI1 expression in osteosarcoma tissue was higher compared with in the paraneoplastic tissue samples. Knockdown of MSI1 using shRNA in MG-63 and HOS cells inhibited cell proliferation
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.