Evidence map›Paper›PMID 29113124›Full record

ReviewInternational journal of molecular sciences2017

Role of Placental VDR Expression and Function in Common Late Pregnancy Disorders.

Julia Knabl, Aurelia Vattai, Yao Ye, Julia Jueckstock, Stefan Hutter, Franz Kainer, Sven Mahner, Udo Jeschke

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
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  12. Article
  13. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. The Significance ofDiagnostics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Julia KnablDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. Julia.knabl@gmx.de.
Aurelia VattaiDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. Aurelia.vattai@med.uni-muenchen.de.
Yao YeDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. yao.ye@med.uni-muenchen.de.
Julia JueckstockDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. julia.jueckstock@med.uni-muenchen.de.
Stefan HutterDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. Stefan.hutter@med.uni-muenchen.de.
Franz KainerDepartment of Obstetrics and Gynecology, Klinik Hallerwiese, 90419 Nürnberg, Germany. franz.kainer@diakonieneuendettelsau.de.
Sven MahnerDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. sven.mahner@med.uni-muenchen.de.
Udo JeschkeDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians Universität München, 80337 Munich, Germany. udo.jeschke@med.uni-muenchen.de.ORCID 0000-0003-2623-3235
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D, besides its classical role in bone metabolism, plays a distinct role in multiple pathways of the feto-maternal unit. Calcitriol is the major active ligand of the nuclear vitamin D receptor (VDR). The vitamin D receptor (VDR) is expressed in different uteroplacental parts and exerts a variety of functions in physiologic pregnancy. It regulates decidualisation and implantation, influences hormone secretion and placental immune modulations. This review highlights the role of the vitamin D receptor in physiologic and disturbed pregnancy, as preeclampsia, fetal growth restriction, gestational diabetes and preterm birth. We discuss the existing literature regarding common VDR polymorphisms in these pregnancy disorders.

Indexed as

CalcitriolDiabetes, GestationalFemaleHumansPolymorphism, GeneticPregnancyReceptors, CalcitriolVitamin DCalcitriolReceptors, CalcitriolVDR protein, humanVitamin Dfetal growth restrictionGDMpreeclampsiapreterm birthVDRvitamin D

Identifiers

PMID29113124
PMCPMC5713309
OpenAlexW2767407320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.