ArticleUltrasonography (Seoul, Korea)2018
Role of core needle biopsy as a first-line diagnostic tool for thyroid nodules: a retrospective cohort study.
Article in Ultrasonography (Seoul, Korea), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of Diagnostic Accuracy of Thyroid Cancer With Ultrasound-Guided Fine-Needle Aspiration and Core-Needle Biopsy: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2020Pooled it
- Gray zone possibility in repeat Bethesda III cytology: a retrospective cohort study of malignancy and multifocality in thyroid nodules.Annals of surgical treatment and research · 2026Article
- Imaging Assessment and Management of Pediatric Thyroid Nodules: Emphasis on Application of 2021 K-TIRADS.Journal of the Korean Society of Radiology · 2026Review
- Advantages of thyroid core needle biopsy: an emerging selective first-line biopsy modality.Ultrasonography (Seoul, Korea) · 2026Article
- Core needle biopsy as a first-line diagnostic tool for selected thyroid nodules: a real-world evaluation of diagnostic performance and safety.Frontiers in oncology · 2026Article
- Comparison of Diagnostic Yield Between Fine Needle Aspiration Cytology and Core Needle Biopsy in the Diagnosis of Thyroid Nodule.Diagnostics (Basel, Switzerland) · 2025Article
- Risk Stratification of Thyroid Nodules Diagnosed as Follicular Neoplasm on Core Needle Biopsy.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Superior Diagnostic Yield of Core Needle Biopsy Over Fine Needle Aspiration in Diagnosing Follicular-Patterned Neoplasms: A Multicenter Study Focusing on Bethesda IV Results.Korean journal of radiology · 2025Article
- A comparative analysis of core needle biopsy and repeat fine needle aspiration in patients with inconclusive initial cytology of thyroid nodules.Frontiers in endocrinology · 2024Article
- Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy.Journal of pathology and translational medicine · 2023Review
- Combined fine-needle aspiration with core needle biopsy for assessing thyroid nodules: a more valuable diagnostic method?Ultrasonography (Seoul, Korea) · 2023Article
- Improvement of Ultrasound Image Quality Using Non-Local Means Noise-Reduction Approach for Precise Quality Control and Accurate Diagnosis of Thyroid Nodules.International journal of environmental research and public health · 2022Article
- Article
- Fine Needle Aspiration Cytology vs. Core Needle Biopsy for Thyroid Nodules: A Prospective, Experimental Study Using Surgical Specimen.Taehan Yongsang Uihakhoe chi · 2022Article
- Analysis of the influencing factors on fine-needle aspiration biopsy results of the thyroid.Frontiers in surgery · 2022Article
- Factors to Consider When Interpreting the Diagnostic Performance of Fine-Needle Aspiration and Core-Needle Biopsy in a Specific Study Population.Yonsei medical journal · 2021Article
- Assessing the diagnostic performance of thyroid biopsy with recommendations for appropriate interpretation.Ultrasonography (Seoul, Korea) · 2021Article
- Author Reply: Factors to Consider When Interpreting the Diagnostic Performance of Fine-Needle Aspiration and Core-Needle Biopsy in Specific Patient Population.Yonsei medical journal · 2021Article
- Usage and Diagnostic Yield of Fine-Needle Aspiration Cytology and Core Needle Biopsy in Thyroid Nodules: A Systematic Review and Meta-Analysis of Literature Published by Korean Authors.Clinical and experimental otorhinolaryngology · 2021Article
- Whirling technique for thyroid fine needle aspiration biopsy: a preliminary study of effectiveness and safety.Ultrasonography (Seoul, Korea) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to evaluate the diagnostic efficacy of fine-needle aspiration (FNA), core needle biopsy (CNB), and combined FNA/CNB for the first-line diagnosis of thyroid nodules.
methodsA total of 782 consecutive nodules that underwent simultaneous FNA and CNB were analyzed in this study. We compared the rate of inconclusive results and the diagnostic values for malignancy among FNA, CNB, and combined FNA/CNB.
resultsCNB showed a lower rate (10.2%) of inconclusive results than FNA (23.7%) (P<0.001). Combined FNA/CNB showed a lower rate (6.5%) of inconclusive results than FNA (all nodules, P<0.001; macronodules, P<0.001; and micronodules, P<0.001, respectively) or CNB (all nodules, P<0.001; macronodules, P<0.001; and micronodules, P=0.003, respectively). Combined FNA/ CNB and CNB showed significantly higher sensitivity, accuracy, and diagnostic performance for malignancy as defined by criterion 1 (Bethesda category VI) or criterion 2 (Bethesda categories IV/V/VI) than FNA (P<0.001). However, there was no significant difference in the sensitivity, accuracy, or diagnostic performance between combined FNA/CNB and CNB (with criterion 1, P=0.063, P=0.063, and P=0.412, respectively; with criterion 2, P=0.500, P=0.500, and P=0.348, respectively).
conclusionCNB was found to be more effective than FNA for the diagnosis of thyroid nodules, and its sensitivity and diagnostic performance for malignancy were similar to those of combined FNA/CNB. CNB has the potential to be an effective alternative first-line diagnostic tool for thyroid nodules when performed by an experienced operator.
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