Evidence map›Paper›PMID 29112170›Full record

ArticleMolecules (Basel, Switzerland)2017

PSN-PC: A Novel Antimicrobial and Anti-Biofilm Peptide from the Skin Secretion of Phyllomedusa-camba with Cytotoxicity on Human Lung Cancer Cell.

Xianhui Wu, Jinhuo Pan, Yue Wu, Xinping Xi, Chengbang Ma, Lei Wang, Mei Zhou, Tianbao Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xianhui WuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210000, China. wxhui2013@163.com.
Jinhuo PanSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210000, China. panjinhuonj@163.com.
Yue WuNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. ywu16@qub.ac.uk.
Xinping XiNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. x.xi@qub.ac.uk.
Chengbang MaNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. c.ma@qub.ac.uk.
Lei WangNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. l.wang@qub.ac.uk.
Mei ZhouNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. m.zhou@qub.ac.uk.
Tianbao ChenNatural Drug Discovery Group, School of Pharmacy, Queen's University, Belfast BT9 7BL, Northern Ireland, UK. t.chen@qub.ac.uk.
Queen's University Belfast · GBNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides derived from amphibian skin secretion are promising drug prototypes for combating widespread infection. In this study, a novel peptide belonging to the phylloseptin family of antimicrobial peptides was isolated from the skin secretion of the

Indexed as

Antimicrobial Cationic PeptidesAntineoplastic AgentsBiofilmsCandida albicansCarcinoma, Non-Small-Cell LungCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorEscherichia coliHumansLung NeoplasmsMethicillin-Resistant Staphylococcus aureusPseudomonas aeruginosaStaphylococcus aureusAntimicrobial Cationic PeptidesAntineoplastic AgentsPhyllosetin-PBa, Phyllomedusa balteaanti-biofilm activityantimicrobial peptidecancer cell cytotoxicityphylloseptin

Identifiers

PMID29112170
PMCPMC6150266
OpenAlexW2767969544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.