Evidence map›Paper›PMID 29112144›Full record

ArticleMarine drugs2017

Evidence for a Saponin Biosynthesis Pathway in the Body Wall of the Commercially Significant Sea Cucumber Holothuria scabra.

Shahida Akter Mitu, Utpal Bose, Saowaros Suwansa-Ard, Luke H Turner, Min Zhao, Abigail Elizur, Steven M Ogbourne, Paul Nicholas Shaw, Scott F Cummins

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Metabolomic profiling ofComputational and structural biotechnology journal · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Antioxidant and Anti-inflammatory Activity of Sea Cucumber (Bioinformatics and biology insights · 2023
    Article
  10. Review
  11. Journal of traditional and complementary medicine · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shahida Akter MituGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. s_m169@student.usc.edu.au.
Utpal BoseGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. ubose@usc.edu.au.
Saowaros Suwansa-ArdGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. maiky865@gmail.com.
Luke H TurnerGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. luket@tasmanianseafoods.com.au.
Min ZhaoGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. mzhao@usc.edu.au.
Abigail ElizurGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. gaya.elizur@gmail.com.
Steven M OgbourneGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. sogbourn@usc.edu.au.ORCID 0000-0001-9812-4367
Paul Nicholas ShawSchool of Pharmacy, The University of Queensland, Brisbane 4067, Queensland, Australia. n.shaw@uq.edu.au.
Scott F CumminsGenecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia. scummins@usc.edu.au.
University of the Sunshine Coast · AUCommonwealth Scientific and Industrial Research Organisation · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sea cucumber (phylum Echinodermata) body wall is the first line of defense and is well known for its production of secondary metabolites; including vitamins and triterpenoid glycoside saponins that have important ecological functions and potential benefits to human health. The genes involved in the various biosynthetic pathways are unknown. To gain insight into these pathways in an echinoderm, we performed a comparative transcriptome analysis and functional annotation of the body wall and the radial nerve of the sea cucumber

Indexed as

AnimalsChromatography, LiquidGene Expression RegulationHolothuriaMass SpectrometryMetabolomeRNASaponinsRNASaponinsbiosynthesisbody wallHolothuriasaponinsea cucumber

Identifiers

PMID29112144
PMCPMC5706039
OpenAlexW2767794376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.