ArticleeLife2017
Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 75 citations in OpenAlex.
- Somatic gene repression ensures physical segregation of germline and soma in Drosophila embryos.EMBO reports · 2026Article
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- From embryos to condensates: A developmental biologist's journey.Journal of molecular biology · 2025Article
- Notch controls APC/CScience advances · 2025Article
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- How germ granules promote germ cell fate.Nature reviews. Genetics · 2024Review
- Widespread regulation of the maternal transcriptome by Nanos in Drosophila.PLoS biology · 2024Article
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- Caenorhabditis elegans germ granules accumulate hundreds of low translation mRNAs with no systematic preference for germ cell fate regulators.Development (Cambridge, England) · 2024Article
- P-body-like condensates in the germline.Seminars in cell & developmental biology · 2024Review
- Characterization of the distribution and dynamics of chromatin states in theGenome research · 2024Article
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- Organogenetic transcriptomes of the Drosophila embryo at single cell resolution.Development (Cambridge, England) · 2024Article
- Epigenetic dynamics during germline development: insights from Drosophila and C. elegans.Current opinion in genetics & development · 2023Review
- Widespread transposon co-option in theScience advances · 2022Article
- Specialized germline P-bodies are required to specify germ cell fate in Caenorhabditis elegans embryos.Development (Cambridge, England) · 2022Article
- Germline immortality relies on TRIM32-mediated turnover of a maternal mRNA activator inScience advances · 2022Article
- Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrest.Cell reports · 2022Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Nanos RNA-binding proteins are required for germline development in metazoans, but the underlying mechanisms remain poorly understood. We have profiled the transcriptome of primordial germ cells (PGCs) lacking the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.